Heart fix may stop migraines: new trial tests Hole-Closing procedure
NCT ID NCT07170176
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether closing a small hole in the heart (called a PFO) can reduce migraine attacks and improve brain function. Researchers will compare 150 adults with migraines and a PFO who get the closure procedure to those who don't. The goal is to see if the procedure cuts monthly migraine days and eases pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Percutaneous patent foramen ovale closure device
What this could lead to
If it works, this could point toward a non-drug treatment for migraines in people with a common heart defect.
What could go wrong
This is a small, early-stage study with no control group for the procedure, so results may not be conclusive. The procedure itself carries risks like bleeding or device complications.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Luoyang Central Hospital
RECRUITINGLuoyang, Henan, 471009, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Second Hospital of Tianjin Medical University
RECRUITINGTianjin, Tianjin Municipality, 300211, China
Contact Phone: •••-•••-•••• Email: •••••@•••••