PATENT FORAMEN OVALE
Clinical trials for PATENT FORAMEN OVALE explained in plain language.
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New device aims to seal heart hole and prevent second strokes
Disease control Not yet recruitingThis study compares two medical devices used to close a small hole in the heart called a PFO, which can cause strokes. About 1,260 adults who have had a stroke or mini-stroke in the past year will be randomly assigned to receive either the Cocoon PFO Occluder or the Amplatzer PFO…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Giuseppe Tarantini • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Heart procedure may offer lasting migraine relief, new study hopes to prove
Symptom relief Not yet recruitingThis study looks at people with migraines who also have a small hole in the heart (PFO). Participants first take a blood-thinning drug (prasugrel) to see if their migraines improve. Those who respond are randomly assigned to either continue the drug alone or have a procedure to c…
Matched conditions: PATENT FORAMEN OVALE
Phase: PHASE3 • Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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New heart camera aims to make procedures safer
Knowledge-focused Not yet recruitingThis study will test a new ultrasound catheter called VeriSight Pro that takes pictures from inside the heart. Doctors will use it during procedures like closing a hole in the heart or fixing a valve. The goal is to see if it helps guide these procedures safely and effectively. A…
Matched conditions: PATENT FORAMEN OVALE
Sponsor: Philips Clinical & Medical Affairs Global • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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Heart hole closure may rewire migraine brains, study hints
Knowledge-focused Not yet recruitingThis study looks at 45 adults with migraine and a small hole in the heart (PFO). Researchers will use brain scans and thinking tests to see if closing the hole changes brain activity, mood, and migraine symptoms over a year. The goal is to understand the link between PFO and migr…
Matched conditions: PATENT FORAMEN OVALE
Sponsor: Second Xiangya Hospital of Central South University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC