Heart procedure may offer lasting migraine relief, new study hopes to prove

NCT ID NCT07629635

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at people with migraines who also have a small hole in the heart (PFO). Participants first take a blood-thinning drug (prasugrel) to see if their migraines improve. Those who respond are randomly assigned to either continue the drug alone or have a procedure to close the hole plus the drug. After stopping the drug, researchers check if the closure group has fewer migraines. The goal is to find a lasting treatment for migraine sufferers.

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Conditions

The condition(s) this trial relates to.

migraine disorder migraine with aura migraine without aura patent foramen ovale

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Medical Center

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact