Heart procedure may offer lasting migraine relief, new study hopes to prove

This study looks at people with migraines who also have a small hole in the heart (PFO). Participants first take a blood-thinning drug (prasugrel) to see if their migraines improve. Those who respond are randomly assigned to either continue the drug alone or have a procedure to close the hole plus the drug. After stopping the drug, researchers check if the closure group has fewer migraines. The goal is to find a lasting treatment for migraine sufferers.