New device aims to seal heart holes and prevent strokes
NCT ID NCT06120270
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study follows 180 people who receive the CeraFlex PFO Closure System, a device that closes a small hole in the heart called a patent foramen ovale (PFO). The goal is to see how well the device works in everyday medical practice, especially for patients with migraines or strokes linked to PFO. Researchers will track procedure success and any leftover shunts after the device is placed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CeraFlex PFO Closure System (a device implanted to close a hole in the heart)
What this could lead to
If successful, this could confirm that the CeraFlex device safely and effectively closes PFO, reducing the risk of stroke and migraine in patients.
What could go wrong
This is an observational study, not a controlled trial, so results may not prove the device is better than other treatments. Risks include device complications or incomplete closure.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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ASAN Medical Center
RECRUITINGSeoul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Catholic University of Korea St. Vincent's Hospital
RECRUITINGSuwon, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Chonnam National University Hospital
RECRUITINGGwangju, Gwangju, 57393, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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German Heart Center Leipzig
RECRUITINGLeipzig, Germany
Contact
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German Heart Center Munich
RECRUITINGMunich, Germany
Contact
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Heart Center Dresden
NOT_YET_RECRUITINGDresden, Germany
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Herzzentrum Trier
RECRUITINGTrier, Germany
Contact
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Hospital Fürth
RECRUITINGFürth, Germany
Contact
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Kardiologisch-Angiologische Praxis - Herzzentrum Bremen
RECRUITINGBremen, Germany
Contact
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Kath. Marienkrankenhaus gGmbH
RECRUITINGHamburg, Germany
Contact
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Klinikum St. Georg gGmbH Leipzig
NOT_YET_RECRUITINGLeipzig, Germany
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Samsung Medical Center
RECRUITINGSeoul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University clinic Tübingen
RECRUITINGTübingen, Germany
Contact
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Universitätsklinikum Hamburg-Eppendorf (UKE)
RECRUITINGHamburg, Germany
Contact
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Yeungnam University Medical Center
RECRUITINGDaegu, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••