PANCREATIC NEOPLASMS

This study tested whether adding a Chinese herbal formula (QingyiHuaji) to standard chemotherapy helps people with stage IV pancreatic cancer live longer. About 305 adults with advanced pancreatic cancer were randomly assigned to receive either the herbal formula plus chemo or a …

This phase 2 trial tested a combination of chemotherapy drugs given directly into the liver artery for people with pancreatic cancer that had spread only to the liver and stopped responding to standard treatment. The 40 participants received a mix of oxaliplatin, irinotecan lipos…

This study looked at the safety of LYNPARZA (olaparib) when used as a maintenance treatment after platinum-based chemotherapy in 130 patients with BRCA-mutated pancreatic cancer that could not be surgically removed. Researchers tracked side effects like bone marrow problems, lung…

This pilot study tested a highly targeted form of radiation called stereotactic body radiation therapy (SBRT) in 36 patients with pancreatic cancer that could not be removed by surgery or had come back after other treatments. The main goal was to see how safe the treatment was by…

This early-phase study tested whether adding high-dose vitamin C (ascorbate) to standard chemotherapy and radiation is safe for people with pancreatic cancer. Sixteen adults with pancreatic cancer took part. The main goal was to see how many serious side effects occurred, with a …

This study tested two types of endoscopes used in ERCP, a procedure to treat bile duct and pancreas problems. One scope had a single-use plastic cover on its tip, while the other was a standard reusable scope. Researchers compared how well each worked and how often complications …

This study tested a newer biopsy method called fine-needle biopsy (FNB) for diagnosing pancreatic masses. Researchers wanted to see if FNB could provide better tissue samples than the standard fine-needle aspiration (FNA) without needing a cytologist on site. Fifty-two adults wit…

This study looked at how safe and effective a precise type of radiation therapy (SBRT) is for treating liver tumors, liver metastases, and pancreatic tumors. It involved 65 adult patients who were already scheduled for SBRT. The goal was to monitor and improve the treatment proce…

This study looked at whether it is safe and possible to grow mini-tumors (organoids) from pancreatic cancer samples in the lab. 60 patients with pancreatic cancer provided tumor tissue during surgery or biopsy. The goal was to see if these organoids could be used to test differen…

This study tested whether removing surgical drains early (4 days after surgery) instead of the usual 10-15 days reduces infections after pancreaticoduodenectomy, a major operation for pancreatic tumors. 141 patients were included, and those without a pancreatic leak were randomly…