PANCREATIC NEOPLASMS

This study tests an experimental drug called 9-ING-41, which blocks a protein (GSK-3β) that helps cancers grow. It is given alone or with chemotherapy to 350 adults with advanced or hard-to-treat cancers like pancreatic, breast, lung, or bone cancer. The goal is to see if the dru…

This early-phase study tests a new treatment called EGFR-BATs for people with advanced pancreatic cancer that has not responded to standard chemotherapy. The treatment uses the patient's own immune cells, which are trained in a lab to better attack cancer cells. The main goal is …

This early-stage study tests the safety of a new drug, PF-08046049/SGN-BB228, in people with advanced melanoma and other solid tumors that have spread or are hard to treat. The study involves 41 participants and will look at side effects and the right dose. It is not expected to …

This study tests a combination of three drugs (surufatinib, sintilimab, and AG) as a first treatment for people with advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combination can shrink tumors or slow the disease. The study includes 32 a…

This study looks at new ways to diagnose cancer in the bile ducts or pancreas by testing bile and blood for special markers. Researchers will compare these new tests with standard methods to see which works best. About 500 adults with suspected bile duct or pancreatic disease wil…

This study looks at how end-stage kidney disease affects recovery after pancreatic surgery. Researchers will review medical records from 100 patients to see how kidney failure severity and dialysis use impact complications, hospital stay, and costs. The goal is to provide better …

This study tests a thin monitoring probe placed near the surgical site after pancreatic cancer surgery. The probe measures substances like lactic acid and glycerol to detect internal leaks early, before the patient becomes seriously ill. About 200 adults having this surgery will …