PANCREAS CANCER

This early-stage trial tested a personalized vaccine made from unique markers in each patient's tumor. The vaccine was given to 33 people with pancreatic cancer after chemotherapy and before or after surgery. The main goal was to check safety and see if the vaccine boosted the im…

This early-stage trial tested a new type of cancer vaccine in 10 people with advanced cancers of the esophagus, pancreas, liver, or ovaries. The vaccine was made from each patient's own immune cells and designed to help their body fight the tumor. The main goals were to see if th…

This study tested a combination of two oral chemotherapy drugs, vemurafenib and sorafenib, in 10 people with advanced pancreatic cancer that has a specific genetic change called a KRAS mutation. All participants had already tried at least two standard treatments without success. …

This early-phase study tested whether adding the drug anakinra to standard chemotherapy is safe for people with advanced pancreatic cancer that has spread. Thirteen adults with metastatic pancreatic cancer took part. The main goal was to check for side effects and serious adverse…

This study looked at nearly 1,000 adults having pancreatic surgery to see which antibiotic, cefoxitin or piperacillin-tazobactam, works better at preventing wound infections within 30 days after the operation. Participants received one of the two antibiotics before surgery. The g…

This study tested a combination of two drugs, pembrolizumab (an immunotherapy) and azacitidine (a drug that affects gene activity), in people with advanced pancreatic cancer that had worsened after initial treatment. The goal was to see if this combination could help control the …

This early-phase study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle form of a chemotherapy agent, given by IV, to see if it is safe…

This study tested a new treatment plan for people with advanced pancreatic cancer that has spread. It combined chemotherapy with drugs that change how genes work and boost the immune system. The goal was to see if this approach is safe and can help control the disease. 75 patient…

This study tested a new drug called CBX-12 in 69 adults with advanced solid tumors (like ovarian, lung, breast, or colon cancer) that had stopped responding to standard treatments. The goal was to find a safe dose and see if the drug could shrink tumors. The trial was early-stage…

This study looked at 58 people having surgery for suspected pancreatic cancer. Researchers measured immune markers before and after surgery to see if they could predict complications like low blood pressure or infections. The goal is to better understand how the immune system aff…

This study tested a digital chatbot (called CATALYST) to help cancer survivors learn about genetic testing for inherited cancer risk. Fifty adults who had certain cancers (like breast, ovarian, or prostate) used the chatbot or received usual care. The goal was to see if the chatb…

This study looked at whether it is safe and possible to grow mini-tumors (organoids) from pancreatic cancer samples in the lab. Researchers took small tissue samples from 60 patients and tried to grow organoids to test different chemotherapy drugs. The goal was to see if this pro…

This study tested a home monitoring system for people with advanced pancreatic cancer receiving a strong chemotherapy called mFOLFIRINOX. The system tracked symptoms, weight, sleep, and activity to spot early signs of serious side effects. The goal was to see if remote monitoring…