New nanoparticle drug shows promise in early trial for Hard-to-Treat cancers

NCT ID NCT04640480

First seen Jan 28, 2026 · Last updated May 08, 2026 · Updated 18 times

Summary

This early-phase study tested a new drug called SNB-101 in 21 people with advanced solid tumors (like colorectal, breast, or lung cancer) that had stopped responding to standard treatments. The drug is a nanoparticle version of SN-38, a chemotherapy agent, given by IV on days 1 and 15 of each 28-day cycle. The main goal was to find the safest dose and understand side effects, not to cure the cancer.

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Contacts and locations

Locations

  • CHA Medical Center

    Seongnam-si, Gyeonggi-do, 13496, South Korea

  • The Catholic University of Korea Seoul ST. Mary's Hospital

    Seoul, Seoul, 06591, South Korea

  • The Severance Hospital of the Yonsei University

    Seoul, Seoul, 03722, South Korea

Conditions

Explore the condition pages connected to this study.