OSTEOARTHRITIS (OA) OF THE KNEE
Clinical trials for OSTEOARTHRITIS (OA) OF THE KNEE explained in plain language.
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New injection shows promise for Worn-Out knees
Disease control OngoingThis study is testing whether four weekly injections of an experimental drug called TPX-100 can help people with knee arthritis. Researchers will compare TPX-100 to placebo injections in 270 adults aged 50-80 over 53 weeks. The main goals are to check if the treatment is safe and…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE2 • Sponsor: OrthoTrophix, Inc • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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One-Shot gene therapy tested for chronic knee pain
Symptom relief OngoingThis study is testing a single injection of an investigational gene therapy called PCRX-201 for people with painful knee osteoarthritis. The main goal is to see if different doses are safe and well-tolerated over one year, while also exploring if the treatment can reduce knee pai…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE2 • Sponsor: Pacira Pharmaceuticals, Inc • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Freeze your knee pain? new cold injection therapy tested
Symptom relief OngoingThis study is testing whether a new injectable cold energy treatment, called Neural Ice, can help manage chronic pain from knee osteoarthritis. It involves 263 adults aged 22-80 who have not found relief from standard treatments like pain pills or physical therapy. Researchers wi…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: Brixton Biosciences, Inc. • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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New knee brace and 'Blood Flow' training aim to ease arthritis pain
Symptom relief ENROLLING_BY_INVITATIONThis study is testing whether a new type of knee brace and a special muscle training method can help people with knee osteoarthritis. The research will compare the new brace to a traditional one and see if the training improves leg strength and knee function. The goal is to find …
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: China Medical University Hospital • Aim: Symptom relief
Last updated Mar 27, 2026 12:41 UTC
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Hands-On vs. standard therapy: which works better for aching knees?
Symptom relief OngoingThis study compares two physical therapy methods for people with moderate knee arthritis. One approach uses hands-on joint and tissue manipulation, while the other uses traditional exercises and pain-relief devices. Researchers will measure which method better reduces pain and im…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: Ibadat International University, Islamabad • Aim: Symptom relief
Last updated Mar 24, 2026 12:02 UTC