OSTEOARTHRITIS (OA) OF THE KNEE
Clinical trials for OSTEOARTHRITIS (OA) OF THE KNEE explained in plain language.
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New knee injection aims to ease arthritis pain and improve mobility
Disease control OngoingThis study tests whether injections of a drug called TPX-100 can safely reduce pain and improve function in people with mild to severe knee osteoarthritis. About 270 adults aged 50 to 80 will receive either TPX-100 or a placebo shot into the knee joint and be followed for 53 week…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE2 • Sponsor: OrthoTrophix, Inc • Aim: Disease control
Last updated May 17, 2026 06:46 UTC
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New painkiller aims to replace opioids after knee surgery
Symptom relief ENROLLING_BY_INVITATIONThis study compares a new pain medicine called suzetrigine to the standard opioid oxycodone for pain after total knee replacement. About 140 adults with knee osteoarthritis will take either suzetrigine or oxycodone for two weeks after surgery. Researchers will measure pain levels…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated May 17, 2026 06:50 UTC
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Freeze your knee pain away? new study tests cold injection for arthritis
Symptom relief OngoingThis study tests a new injectable cold energy treatment called Neural Ice for chronic knee pain caused by osteoarthritis. About 263 adults aged 22 to 80 with moderate to severe pain will receive the treatment and be followed for 6 months. The goal is to see if it safely reduces p…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: Brixton Biosciences, Inc. • Aim: Symptom relief
Last updated May 17, 2026 06:50 UTC
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One-Shot knee treatment could ease arthritis pain for years
Symptom relief OngoingThis study tests a single injection of an experimental drug called PCRX-201 for people with painful knee osteoarthritis. About 135 adults aged 45 to 80 will receive either a low dose, a high dose, or a placebo to see if it is safe and helps reduce pain and improve knee function. …
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE2 • Sponsor: Pacira Pharmaceuticals, Inc • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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New knee brace and smart exercise offer hope for osteoarthritis sufferers
Symptom relief ENROLLING_BY_INVITATIONThis study tests a new knee brace designed to correct alignment and reduce joint pressure, along with a special low-intensity muscle training method that uses pressure bands. Researchers will compare the new brace to a traditional one in 40 volunteers over 50 with knee osteoarthr…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: China Medical University Hospital • Aim: Symptom relief
Last updated May 11, 2026 20:37 UTC