OSTEOARTHRITIS (OA) OF THE KNEE
Clinical trials for OSTEOARTHRITIS (OA) OF THE KNEE explained in plain language.
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Could this daily pill slow knee arthritis?
Disease control Not yet recruitingThis study tests a drug called Mobithron Advance in people over 50 with mild to moderate knee osteoarthritis. The goal is to see if taking it daily for a year can slow cartilage loss and reduce pain. Participants will have MRI scans and pain checks every few months. The drug is c…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: EARLY_PHASE1 • Sponsor: Universiti Sains Malaysia • Aim: Disease control
Last updated May 17, 2026 05:48 UTC
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Could a diabetes drug help obese patients bounce back faster from knee surgery?
Disease control Not yet recruitingThis study tests whether a weight-loss drug (GLP-1 RA) can improve recovery in obese patients awaiting total knee replacement. About 54 participants will receive the drug or standard care before and after surgery. The goal is to see if losing weight beforehand reduces pain and co…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: EARLY_PHASE1 • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated May 17, 2026 05:34 UTC
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Knee replacement patients may get better pain relief with simple injection
Symptom relief Not yet recruitingThis study tests whether a numbing injection around the knee nerves, given before surgery, can lower pain and the need for strong painkillers after knee replacement. About 70 adults with knee arthritis will be randomly assigned to get either the nerve block or a placebo injection…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: Helse Møre og Romsdal HF • Aim: Symptom relief
Last updated May 17, 2026 05:50 UTC
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Keto diet tested for joint pain and brain fog
Symptom relief Not yet recruitingThis study looks at whether a carefully planned ketogenic diet can reduce pain and improve thinking in people who have both osteoarthritis and mild cognitive impairment. Ten adults will follow the diet under supervision, and researchers will check their pain, physical function, a…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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New painkiller aims to cut opioid use after knee surgery
Symptom relief Not yet recruitingThis study looks at whether a long-acting painkiller called Bupivacaine-Meloxicam can help people who have robot-assisted knee replacement surgery. About 150 adults with knee osteoarthritis will take part. The goal is to see if this medicine reduces pain and the need for opioid p…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Needle phobia? study tests tricks to ease knee injection pain
Symptom relief Not yet recruitingThis study looks at ways to make knee steroid injections less painful for people with knee osteoarthritis. Researchers will test if using a smaller needle or a cooling spray (ethyl chloride) before the shot reduces pain. About 88 adults will rate their pain right after the inject…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated May 13, 2026 16:03 UTC
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Robotic knee surgery showdown: can skipping the scan still deliver?
Symptom relief Not yet recruitingThis study compares two types of robotic-assisted knee replacement surgery for people with severe knee arthritis. One method uses a CT scan to plan the surgery, while the other does not. The goal is to see if the no-scan method works just as well for improving knee pain and funct…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: Medical University of Warsaw • Aim: Symptom relief
Last updated Apr 30, 2026 15:51 UTC
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New study investigates whether running helps or hurts arthritic knees
Knowledge-focused Not yet recruitingThis study looks at how starting a running program affects knee health in people with knee osteoarthritis (OA). Researchers will use MRI scans to measure changes in knee cartilage over time. The goal is to understand if recreational running is safe for those with knee OA. Partici…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC