OSTEOARTHRITIS (OA) OF THE KNEE
Clinical trials for OSTEOARTHRITIS (OA) OF THE KNEE explained in plain language.
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Weight loss shot before knee surgery: could it cut complications?
Disease control Not yet recruitingThis study is testing if using a weight loss medication (semaglutide) before total knee replacement surgery can lead to better outcomes for patients who are obese. It will involve 54 people with knee arthritis who are scheduled for surgery. The main goal is to see if this approac…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: EARLY_PHASE1 • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New drug trial aims to slow knee arthritis damage
Disease control Not yet recruitingThis early-stage study will test whether taking the drug Mobithron Advance daily for one year can slow the progression of knee osteoarthritis and help preserve cartilage. Researchers will follow 84 adults over 50 with mild to moderate knee arthritis, using MRI scans to measure ca…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: EARLY_PHASE1 • Sponsor: Universiti Sains Malaysia • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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Fat-Fueled diet tested to fight pain and brain fog
Symptom relief Not yet recruitingThis study is testing if a supervised ketogenic diet (a very low-carb, high-fat eating plan) can help reduce pain and improve thinking in older adults who have both osteoarthritis and mild memory problems. Ten participants will follow the diet, and researchers will check their pa…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Apr 02, 2026 00:26 UTC
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New injection aims to cut opioid use after knee surgery
Symptom relief Not yet recruitingThis study is looking at a long-acting pain injection (Zynrelef) given during robotic knee replacement surgery. The goal is to see if it helps patients have less pain and need fewer opioid painkillers in the first three days after surgery compared to standard pain injections. Res…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Could a thinner needle make your knee shot hurt less?
Symptom relief Not yet recruitingThis study aims to make steroid injections for knee arthritis less painful. Researchers will test if using a thinner needle or a cooling numbing spray reduces pain during the procedure for 88 participants. They will also check if experiencing less pain from the shot itself leads …
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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New pill aims to beat opioids for surgery pain
Symptom relief Not yet recruitingThis study is testing if a new oral medication called suzetrigine works as well as or better than the standard opioid oxycodone for pain after knee replacement surgery. Researchers want to see if suzetrigine can control pain effectively while reducing the total amount of opioid m…
Matched conditions: OSTEOARTHRITIS (OA) OF THE KNEE
Phase: PHASE4 • Sponsor: University of Louisville • Aim: Symptom relief
Last updated Mar 23, 2026 15:16 UTC