Freeze your knee pain away? new study tests cold injection for arthritis

NCT ID NCT06700109

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 26 times

Summary

This study tests a new injectable cold energy treatment called Neural Ice for chronic knee pain caused by osteoarthritis. About 263 adults aged 22 to 80 with moderate to severe pain will receive the treatment and be followed for 6 months. The goal is to see if it safely reduces pain during activity by at least 30%.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Centers for Advanced Orthopedics

    Washington D.C., District of Columbia, 20036, United States

  • Clinical Investigations, LLC

    Edmond, Oklahoma, 73034, United States

  • Emory University

    Johns Creek, Georgia, 30097, United States

  • Insight Hospital and Medical Center Chicago

    Chicago, Illinois, 60616, United States

  • Insight Research Institute

    Flint, Michigan, 48507, United States

  • Marin Health

    Larkspur, California, 94939, United States

  • NextStage Clinical Research Advanced Orthopaedic Associates

    Wichita, Kansas, 67226, United States

  • NextStage Clinical Research All-American Orthopedic & Sports Medicine Institute

    Houston, Texas, 77058, United States

  • NextStage Clinical Research Regenerative Orthopedics and Sports Medicine

    North Bethesda, Maryland, 20852, United States

  • NextStage Clinical Research The Orthopedic Center

    Tulsa, Oklahoma, 74104, United States

  • Ochsner Health System

    New Orleans, Louisiana, 70115, United States

  • Pain Diagnostics and Interventional Care

    Sewickley, Pennsylvania, 15143, United States

  • The Orthopaedic Institute

    Gainesville, Florida, 32607, United States

  • UT San Antonio

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.