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Cheaper collagen injection could rival standard knee OA treatment

NCT ID NCT07692009

Completed Disease control Sponsor: Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan S. Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This trial tests whether a collagen-based injection (Fibroquel) works as well as a standard hyaluronic acid injection (Synvisc) for knee osteoarthritis. About 32 adults with moderate knee OA will receive three weekly injections of one treatment. The study measures knee function and pain over six months to see if the less expensive collagen option is a good alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
collagen-polyvinylpyrrolidone (collagen-PVP, Fibroquel)
What this could lead to
If collagen-PVP works as well as Synvisc but costs less, it could offer a more affordable option for managing knee osteoarthritis pain and function.
What could go wrong
This is a small, early-phase study with only 32 participants, so results may not apply broadly. Both treatments are injectable and carry risks like joint pain or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OSTEOARTHRITIS (OA) OF THE KNEE

Contacts and locations

Locations

  • Centro Multidisciplinario para el Desarrollo Especializado de la Investigacion Clinica en Yucatan

    Mérida, Yucatán, 97130, Mexico

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