OSTEO ARTHRITIS OF THE KNEE

This study tests whether methotrexate, a drug used for rheumatoid arthritis, can reduce pain and swelling in people with knee osteoarthritis who have joint inflammation seen on ultrasound. About 70 adults aged 40–70 will receive either methotrexate or standard care for 6 months. …

This study tests the safety of a single injection of Hydrogel OA 2% for knee osteoarthritis. About 20 adults aged 35-75 with knee pain will receive the injection and be monitored for side effects for up to 12 months. The goal is to see if the gel is safe and tolerable for easing …

This study looks at whether the BETY exercise program, which combines physical exercises with emotional and social support, can reduce pain and improve quality of life in people with knee osteoarthritis. Participants must have received a knee injection in the past month. The goal…

This study tests a new home device that helps people with knee osteoarthritis improve leg control and reduce pain. Participants sit and use their foot to stabilize a spring-loaded platform, training the nerves and muscles that control the knee. The trial compares this device to s…

This study tests a new, less invasive treatment for people with long-term knee pain from advanced osteoarthritis or pain that continues after knee replacement surgery. The procedure uses a thin tube to deliver a temporary blocking agent to small arteries feeding inflamed knee tis…

This study tests whether a special magnetic therapy (HI-PEMF) can reduce pain and improve strength in older adults with knee osteoarthritis. About 64 people aged 60 and older will receive either joint-only or joint-plus-muscle treatment, plus a home exercise program. The goal is …

This study compares two different nerve block techniques to see which one provides better pain relief after total knee replacement surgery. The goal is to reduce the need for strong painkillers (opioids) and help patients move sooner. About 120 adults having knee replacement will…