OPEN HEART SURGERY
Clinical trials for OPEN HEART SURGERY explained in plain language.
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Heart drug showdown: which works better during bypass surgery?
Disease control CompletedThis study compared two drugs, levosimendan and adrenaline, given during heart bypass surgery to 60 patients with weak hearts (ejection fraction 30-40%). The goal was to see which drug better supports heart function during and right after surgery. Researchers measured heart pumpi…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 17, 2026 07:36 UTC
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New drug may shield kidneys during heart surgery
Disease control CompletedThis study tested a drug called ilofotase alfa in 271 adults who were at risk for kidney damage after open heart surgery. Participants received two doses of the drug or a placebo through a vein. The goal was to see if the drug could keep kidney function stable by measuring creati…
Matched conditions: OPEN HEART SURGERY
Phase: PHASE2 • Sponsor: AM-Pharma • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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New pain block may speed recovery after Open-Heart surgery
Symptom relief CompletedThis study tested a new type of nerve block called SPSIPB to see if it reduces pain and helps people recover faster after open-heart surgery. 70 adults having elective open-heart surgery were randomly assigned to receive either the SPSIPB or standard pain management. The main goa…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Bursa City Hospital • Aim: Symptom relief
Last updated May 12, 2026 13:40 UTC
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Pre-Surgery video eases ICU jitters for heart patients
Symptom relief CompletedThis study looked at whether showing patients a video about what to expect in the intensive care unit (ICU) before their open-heart surgery could lower their anxiety and improve their ICU experience. 110 adults scheduled for planned open-heart surgery took part. The goal was to s…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Zeynep Turak • Aim: Symptom relief
Last updated Apr 26, 2026 20:03 UTC
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New nerve block eases pain after Open-Heart surgery
Symptom relief CompletedThis study tested whether a nerve block called erector spinae plane block (ESPB) can improve pain control and recovery after open-heart surgery. 66 adults were randomly assigned to receive either the nerve block or standard intravenous painkillers. Researchers measured pain score…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Karadeniz Technical University • Aim: Symptom relief
Last updated Apr 26, 2026 19:35 UTC
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Eye ultrasound may help track brain pressure during heart surgery
Knowledge-focused CompletedThis study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery when a heart-lung machine is used. Forty adults having elective heart surgery were enrolled. The goal wa…
Matched conditions: OPEN HEART SURGERY
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated May 17, 2026 07:52 UTC
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Heart surgery drainage showdown: active vs. standard tubes
Knowledge-focused CompletedThis study looked at 250 adults who had heart surgery to see if a special method to keep chest tubes clear (active clearance) works better than standard drainage. The goal was to reduce problems like retained blood, bleeding, and the need for another surgery. Researchers reviewed…
Matched conditions: OPEN HEART SURGERY
Sponsor: Kasr El Aini Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC