OPEN-HEART SURGERY
Clinical trials for OPEN-HEART SURGERY explained in plain language.
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Heart drug showdown: which works better during bypass surgery?
Disease control CompletedThis study compared two medications, levosimendan and adrenaline, given during heart bypass surgery to patients with weak hearts (ejection fraction 30-40%). Sixty adults aged 18-65 having elective surgery were included. The goal was to see which drug better supports heart functio…
Matched conditions: OPEN-HEART SURGERY
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Can a simple infusion shield kidneys during heart surgery?
Disease control CompletedThis study tested whether a drug called ilofotase alfa can prevent kidney damage in people undergoing open heart surgery. 271 patients received either the drug or a placebo before and after surgery. The goal was to see if the drug could keep kidney function stable and reduce seri…
Matched conditions: OPEN-HEART SURGERY
Phase: PHASE2 • Sponsor: AM-Pharma • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New nerve block could ease pain after Open-Heart surgery
Symptom relief CompletedThis study tested a nerve block called SPSIPB to see if it reduces pain and opioid use after open-heart surgery. 70 adults were randomly assigned to receive either the SPSIPB or standard pain management. The goal was to compare pain scores and recovery over 24 hours.
Matched conditions: OPEN-HEART SURGERY
Phase: NA • Sponsor: Bursa City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Heart surgery patients watch video, anxiety may drop
Symptom relief CompletedThis study tested whether showing patients a video about the intensive care unit (ICU) before open-heart surgery could lower their anxiety and improve their ICU experience. 110 adults scheduled for planned open-heart surgery were enrolled. The video was shown 48 hours before surg…
Matched conditions: OPEN-HEART SURGERY
Phase: NA • Sponsor: Zeynep Turak • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New nerve block technique may ease pain after heart surgery
Symptom relief CompletedThis study tested whether a nerve block called erector spinae plane block (ESPB) can improve pain control and recovery in adults undergoing open-heart surgery. Sixty-six participants received either the nerve block or standard IV opioids. Researchers measured pain scores, need fo…
Matched conditions: OPEN-HEART SURGERY
Phase: NA • Sponsor: Karadeniz Technical University • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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New chest tube method may cut complications after heart surgery
Knowledge-focused CompletedThis study looked at two methods of draining blood and fluid from the chest after heart surgery. It compared a newer active clearance method that keeps tubes open with standard passive drainage. Researchers reviewed records of 250 adult patients from three heart surgery centers t…
Matched conditions: OPEN-HEART SURGERY
Sponsor: Kasr El Aini Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Eye ultrasound may help monitor brain pressure during heart surgery
Knowledge-focused CompletedThis study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery when patients are on a heart-lung machine. Researchers measured the optic nerve sheath diameter in 40 ad…
Matched conditions: OPEN-HEART SURGERY
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC