Can a simple infusion shield kidneys during heart surgery?
NCT ID NCT06168799
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether a drug called ilofotase alfa can prevent kidney damage in people undergoing open heart surgery. 271 patients received either the drug or a placebo before and after surgery. The goal was to see if the drug could keep kidney function stable and reduce serious kidney events.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ilofotase alfa
What this could lead to
If it works, this could provide a way to protect kidneys during heart surgery, reducing the risk of long-term kidney problems.
What could go wrong
This is a Phase 2 trial with only 271 participants, so results may not apply to everyone. The drug may not prove effective or could have side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research site
Munich, Germany