OBSTRUCTIVE SLEEP APNEA (OSA)

This study compares two approaches to help people with moderate-to-severe obstructive sleep apnea stay on CPAP therapy. One group receives usual care, where patients reach out if they have trouble. The other group adds active monitoring and extra support only for those who strugg…

This trial investigates whether a single dose of the experimental drug DAW2020, taken before sleep, can improve how the brain responds to airway blockages in people with moderate-to-severe obstructive sleep apnea. The study measures changes in the arousal threshold—the point at w…

This study tests a device that uses freezing (cryoablation) on the tongue and soft palate to treat moderate to severe obstructive sleep apnea. It is for adults aged 22 to 70 who cannot or will not use standard treatments like CPAP or mouthguards. The goal is to see if the procedu…

This study looks at whether using a CPAP machine at night can reduce the chance of atrial fibrillation (an irregular heartbeat) returning in people who have both sleep apnea and a history of AF. Researchers will follow 91 adults for 12 months, tracking how often they use CPAP and…

This study tests whether combining two sedatives, remimazolam and propofol, works better than propofol alone or with midazolam during a procedure called drug-induced sleep endoscopy (DISE) for people with obstructive sleep apnea. The goal is to see if the combo leads to more succ…

This study tests whether doing simple mouth, tongue, and throat exercises using a mobile app can improve snoring and sleep apnea better than following a paper guide. The 34 participants are adults with mild to severe obstructive sleep apnea who could not or would not use a CPAP m…

This observational study looks at adults diagnosed with obstructive sleep apnea (OSA) who visit Sohag University Hospitals. Researchers will examine the severity of their condition, their specific symptoms, and any other health problems they may have. The goal is to build a clear…

This study tests a questionnaire called the PAP Problems Triaging Tool, designed to identify why people with obstructive sleep apnea struggle to use their positive airway pressure (PAP) machines. Researchers will ask adults newly prescribed PAP therapy to complete the questionnai…

This study is testing whether a simple breath test, called fractional exhaled nitric oxide (FeNO), can help measure the severity of obstructive sleep apnea (OSA). Researchers will compare FeNO levels in 200 adults with different levels of sleep apnea to see if the test can predic…

This early study at Mayo Clinic tests whether using a device that massages the legs at night can help the brain clear waste products better in people with obstructive sleep apnea. The study involves 12 adults aged 50 and older who already use CPAP therapy. Researchers will measur…