Could a drug combo make sleep apnea scopes easier?

NCT ID NCT06784479

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining two sedatives, remimazolam and propofol, works better than propofol alone or with midazolam during a procedure called drug-induced sleep endoscopy (DISE) for people with obstructive sleep apnea. The goal is to see if the combo leads to more successful sedation with fewer side effects. About 174 adults with sleep apnea will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Remimazolam and Propofol

What this could lead to

If successful, this could identify a safer, more effective sedation method for diagnosing sleep apnea, improving patient comfort and procedure success.

What could go wrong

This is a small, single-center phase 4 trial focused on sedation during a diagnostic procedure, not a treatment for sleep apnea itself. Results may not apply to other settings or populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for OBSTRUCTIVE SLEEP APNEA (OSA) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Respiratory Endoscopy Center of Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300052, China