Could a drug combo make sleep apnea scopes easier?

NCT ID NCT06784479

Ongoing Symptom relief Sponsor: Dan Liu Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining two sedatives, remimazolam and propofol, works better than propofol alone or with midazolam during a procedure called drug-induced sleep endoscopy (DISE) for people with obstructive sleep apnea. The goal is to see if the combo leads to more successful sedation with fewer side effects. About 174 adults with sleep apnea will take part.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Remimazolam and Propofol
What this could lead to: If successful, this could identify a safer, more effective sedation method for diagnosing sleep apnea, improving patient comfort and procedure success.
What could go wrong: This is a small, single-center phase 4 trial focused on sedation during a diagnostic procedure, not a treatment for sleep apnea itself. Results may not apply to other settings or populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OBSTRUCTIVE SLEEP APNEA (OSA) SEDATIVE EFFECT DURING DRUG-INDUCED SLEEP ENDOSCOPY

Contacts and locations

Locations

Respiratory Endoscopy Center of Tianjin Medical University General Hospital

Tianjin, Tianjin Municipality, 300052, China

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