OBESITY (DISORDER)

This study will test whether timing meals according to a person's natural body clock helps maintain weight loss after bariatric surgery. Researchers will enroll 246 adults who had sleeve gastrectomy at least six months ago and randomly assign them to either standard nutrition adv…

This study aims to find the most effective way to give weekly feedback to people in a weight loss program. About 127 adults with obesity or overweight will track their diet, activity, and weight, and receive weekly messages from a coach. Researchers will test if the tone and cont…

This study is testing if wearing a continuous glucose monitor (CGM) helps people with severe obesity manage their blood sugar better before and after weight-loss surgery, compared to the standard finger-prick method. Researchers will recruit 20 people in Louisiana who are schedul…

This study aims to see if a special diet designed to increase the variety of gut bacteria helps people maintain weight loss after bariatric surgery better than standard dietary advice. It will involve 60 adults who have had weight loss surgery, comparing the two diet approaches o…

This study is exploring whether a weekly medication called tirzepatide is a practical option for helping postmenopausal women who have survived hormone receptor-positive breast cancer and are living with obesity. Researchers want to see if participants can stick with the 6-month …

This study aims to understand how well the medication semaglutide works in everyday life for people with type 2 diabetes or obesity. Researchers will look back at the health records of 400 Canadian patients to compare semaglutide's effects on blood sugar, weight, and heart and ki…

This study aims to understand how obesity and low iron levels affect iron buildup in organs like the liver and heart, and stress in fat cells. Researchers will compare 50 adults with obesity, some with and some without iron deficiency, using MRI scans and fat tissue samples befor…

This study aims to understand how obesity affects acid reflux disease (GERD). Researchers will examine 200 adults with obesity to see how common GERD is in this group and explore the connection. This is an observational study that measures and observes, not a treatment trial.