NSCLC
Clinical trials for NSCLC explained in plain language.
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New drug combo tested for Tough-to-Treat lung cancer
Disease control TerminatedThis early-phase study tested a new combination of two investigational drugs, AK119 and AK112, with or without chemotherapy, for people with advanced non-small cell lung cancer. The cancer had a specific genetic change (EGFR mutation) and had stopped responding to standard target…
Matched conditions: NSCLC
Phase: PHASE1, PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Experimental drug tested for Tough-to-Treat cancers
Disease control TerminatedThis study tested an experimental drug called VLS-101 (zilovertamab vedotin) in 102 people with advanced solid tumors that had spread and stopped responding to previous treatments. The trial aimed to see if the drug could shrink tumors and was safe for cancers including breast, l…
Matched conditions: NSCLC
Phase: PHASE2 • Sponsor: VelosBio Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New targeted drug tested for Tough-to-Treat lung cancers
Disease control TerminatedThis study tested a new type of targeted cancer drug called MYTX-011 in people with advanced non-small cell lung cancer (NSCLC) that had progressed after standard treatments. The main goals were to find a safe dose and see if the drug could shrink tumors, especially in patients w…
Matched conditions: NSCLC
Phase: PHASE1 • Sponsor: Mythic Therapeutics • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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Could a simple blood test replace painful biopsies for lung cancer?
Knowledge-focused TerminatedThis study aimed to see if a simple blood test (liquid biopsy) could be as accurate as a traditional tissue biopsy for finding specific genetic changes in lung cancer. Researchers compared results from both methods in 21 patients with advanced lung cancer who had not yet started …
Matched conditions: NSCLC
Phase: NA • Sponsor: Centre Oscar Lambret • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:41 UTC
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Scientists track cancer drug in blood to predict treatment success
Knowledge-focused TerminatedThis study aimed to understand how the amount of pembrolizumab (an immunotherapy drug) in patients' blood relates to their treatment outcomes. Researchers monitored 80 people with advanced non-small cell lung cancer who were receiving pembrolizumab, either alone or with chemother…
Matched conditions: NSCLC
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC