Lung cancer drug levels under the microscope

NCT ID NCT04557007

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study looked at how much of the immunotherapy drug pembrolizumab stays in the blood of patients with advanced non-small cell lung cancer. Researchers measured drug levels and immune responses in 80 patients receiving pembrolizumab alone or with chemotherapy. The goal was to see if drug concentration relates to how well the cancer responds or to side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

pembrolizumab

What this could lead to

If successful, this study could help doctors personalize pembrolizumab dosing for lung cancer patients, potentially improving outcomes and reducing side effects.

What could go wrong

This is an observational study, not a treatment trial. It was terminated early, so results may be limited and not conclusive.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • St Olavs University Hospital

    Trondheim, Norway