NERVOUS SYSTEM DISEASES

This completed Phase 2 study tested whether the drug XPro1595 could help slow cognitive decline in people with early Alzheimer's disease who show signs of brain inflammation. 208 participants with mild Alzheimer's or mild cognitive impairment received either the drug or a placebo…

This study continued testing an experimental drug called AOC 1001 in adults with myotonic dystrophy type 1, a genetic muscle-wasting disease. It followed 37 participants from a previous trial to check long-term safety and see if the drug continues to work when given every 8 weeks…

This study tested whether a drug called ataluren could slow the progression of muscle weakness in boys with a specific genetic form of Duchenne muscular dystrophy. For 72 weeks, 360 participants received either ataluren or a placebo, followed by another 72 weeks where everyone re…

This large study tested whether sprinkling a powdered antibiotic (vancomycin) directly into the surgical wound during brain surgery could prevent dangerous infections. Over 1,100 adult patients having brain surgery were randomly assigned to receive either this topical antibiotic …

This study tested whether a special suit that delivers mild electrical stimulation could help people with fibromyalgia. Twenty-eight participants wore either an active or inactive version of the suit for two weeks to see if it reduced pain, fatigue, and improved their quality of …

This study aimed to understand how the bodies of elite athletes adapt to intense physical training. Researchers measured a wide range of hormones, markers of fatigue, metabolism, and inflammation in 30 professional rowers before and after exhaustive exercise tests. The goal was t…