NERVOUS SYSTEM DISEASES

This study is testing different dosing schedules for the Alzheimer's drug donanemab to find the best balance between clearing harmful brain plaques and minimizing a serious side effect called ARIA-E, which is brain swelling. It involves about 1,175 adults with early memory proble…

This Phase 3 trial is testing whether a single dose of an experimental gene therapy called NTLA-2001 can safely slow or stop the progression of hereditary amyloidosis with polyneuropathy (ATTRv-PN), a rare genetic disease that damages nerves. About 50 participants worldwide will …

This study is testing whether a cell therapy called deramiocel can slow the loss of muscle function in boys and young men with Duchenne muscular dystrophy (DMD). About 106 participants will receive either the therapy or a placebo via IV infusion every three months for a year, wit…

This study is testing whether the gentle mind-body exercise Tai Chi can help improve chronic insomnia in women who have survived breast cancer. Researchers are comparing Tai Chi to standard cognitive behavioral therapy (CBT) to see which is better at improving sleep quality, redu…

This study is testing a new, more comfortable headset designed to help people with advanced ALS communicate. The device reads brain signals to let users type on a virtual keyboard without moving. Researchers are working with a small group of ALS patients to see if this prototype …