MYELOID MALIGNANCY
Clinical trials for MYELOID MALIGNANCY explained in plain language.
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New hope for hard-to-treat leukemia: triple-drug combo enters phase 2 trial
Disease control Recruiting nowThis study tests a combination of three drugs (mitoxantrone liposome, cytarabine, and venetoclax) in 72 adults with acute myeloid leukemia that has returned or not responded to prior therapy. The goal is to see if this combo can achieve complete remission. Participants will recei…
Matched conditions: MYELOID MALIGNANCY
Phase: PHASE2 • Sponsor: First Affiliated Hospital of Zhejiang University • Aim: Disease control
Last updated May 17, 2026 03:14 UTC
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New Low-Dose combo after transplant aims to stop leukemia relapse
Disease control Recruiting nowThis study tests whether a milder chemotherapy combination (decitabine and venetoclax) given weekly after a bone marrow transplant can help prevent high-risk myeloid cancers like acute myeloid leukemia from coming back. About 20 participants will receive the treatment for up to o…
Matched conditions: MYELOID MALIGNANCY
Phase: PHASE1, PHASE2 • Sponsor: Benjamin Tomlinson • Aim: Disease control
Last updated May 17, 2026 03:13 UTC
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Can a common drug prevent relapse after stem cell transplant?
Disease control Recruiting nowThis study tests whether a low dose of the drug azacitidine can help maintain or increase the level of donor cells in patients with certain blood cancers (MDS, AML, CMML, MPN) after a stem cell transplant. The goal is to reduce the chance of the cancer coming back. About 43 adult…
Matched conditions: MYELOID MALIGNANCY
Phase: PHASE2 • Sponsor: Henry Ford Health System • Aim: Disease control
Last updated May 17, 2026 03:13 UTC
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New hope for hard-to-treat leukemia: experimental drug lisaftoclax enters human testing
Disease control Recruiting nowThis study tests a new drug called lisaftoclax (APG-2575) in people with acute myeloid leukemia (AML) that has returned or not improved with standard treatments. The drug is given alone or together with other medicines (homoharringtonine or azacitidine). The main goals are to che…
Matched conditions: MYELOID MALIGNANCY
Phase: PHASE1, PHASE2 • Sponsor: Ascentage Pharma Group Inc. • Aim: Disease control
Last updated May 04, 2026 16:20 UTC
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New drug combo aims to boost stem cell transplant success for tough blood cancers
Disease control Recruiting nowThis early-stage trial tests whether adding decitabine and venetoclax to a standard stem cell transplant is safe for people with high-risk blood cancers like leukemia. About 20 adults aged 18-75 with a matching donor will take part. The goal is to find the best dose that limits s…
Matched conditions: MYELOID MALIGNANCY
Phase: PHASE1 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 01, 2026 15:57 UTC
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Can a simple skin test reveal your hidden risk for blood cancer?
Knowledge-focused Recruiting nowThis study is testing a new gene panel called MyeloGen to see if it can find inherited genetic risks for myeloid cancers (a type of blood cancer). Researchers will enroll 200 adults with these cancers and take a small skin sample to look for gene changes. The goal is to see if th…
Matched conditions: MYELOID MALIGNANCY
Phase: NA • Sponsor: Christopher Reilly • Aim: Knowledge-focused
Last updated May 17, 2026 03:13 UTC
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Can a simple genetic test catch blood cancers before they start?
Knowledge-focused Recruiting nowThis study uses advanced genetic testing (next generation sequencing) to look for early warning signs of pre-myeloid cancers and bone marrow failure in 2000 people. Participants have certain blood abnormalities or genetic markers that may increase their risk. The goal is to bette…
Matched conditions: MYELOID MALIGNANCY
Phase: NA • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 03:09 UTC
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Digital stories may ease stem cell transplant decisions for blood cancer patients
Knowledge-focused Recruiting nowThis study tests whether watching digital stories from other patients helps people with myeloid cancers (like AML or MDS) make decisions about a stem cell transplant. About 120 adults will either watch these stories or receive usual care. The goal is to see if this approach is pr…
Matched conditions: MYELOID MALIGNANCY
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Telehealth tool aims to ease tough talks for older cancer patients
Knowledge-focused Recruiting nowThis study tests a telehealth program to help older adults (60+) with blood cancers like leukemia talk with their doctors about their care wishes. It aims to reduce anxiety and improve completion of advance directives. About 207 patients and their caregivers will participate remo…
Matched conditions: MYELOID MALIGNANCY
Phase: NA • Sponsor: University of Rochester • Aim: Knowledge-focused
Last updated May 08, 2026 12:01 UTC