METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Clinical trials for METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA explained in plain language.
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New hope for pancreatic cancer: drug combo shows promise in early trial
Disease control OngoingThis study tests two experimental drugs (AK112 and cadonilimab) plus standard chemotherapy as a first treatment for people with stage IV pancreatic cancer. About 110 adults aged 18-75 who have not had prior treatment will participate. The goal is to see if the combination is safe…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Akeso • Aim: Disease control
Last updated May 16, 2026 22:33 UTC
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New hope for tough-to-treat pancreatic cancer: drug duo tested
Disease control OngoingThis study tests a combination of two drugs (BXCL701 and pembrolizumab) in 22 people with advanced pancreatic cancer that has spread. The goal is to see if this treatment can stop the cancer from growing for at least 18 weeks. Participants must be willing to have two tumor biopsi…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Georgetown University • Aim: Disease control
Last updated May 16, 2026 22:31 UTC
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New drug combo shows promise for tough pancreatic cancer
Disease control OngoingThis study tests whether combining two drugs, pembrolizumab (which helps the immune system fight cancer) and olaparib (which stops cancer cells from repairing themselves), can help people with metastatic pancreatic cancer that has a specific genetic feature or has responded well …
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 16, 2026 22:31 UTC
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Can a common diabetes pill help pancreatic cancer patients manage blood sugar?
Disease control OngoingThis study looks at how safe and effective the diabetes drug glipizide is for lowering blood sugar in people with pancreatic cancer. About 29 adults with active pancreatic cancer and high blood sugar will take glipizide, and their glucose levels will be measured before and after …
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 16, 2026 22:30 UTC
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New hope for pancreatic cancer: experimental drug combo tested in large trial
Disease control OngoingThis phase 3 trial tests whether adding the experimental drug quemliclustat to standard chemotherapy helps people with metastatic pancreatic cancer live longer. About 610 participants who have not yet been treated for advanced disease will receive either the drug combo or a place…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: Arcus Biosciences, Inc. • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for pancreatic cancer? trial adds immunotherapy to chemo
Disease control OngoingThis study tests whether adding a new immunotherapy drug called botensilimab to standard chemotherapy works better than chemotherapy alone for people with metastatic pancreatic cancer that has worsened after initial treatment. About 81 participants will be randomly assigned to on…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Agenus Inc. • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Sound waves boost chemo in tough pancreatic cancer trial
Disease control OngoingThis study tests a technique called sonoporation, which uses ultrasound and tiny bubbles to help chemotherapy drugs get into cancer cells more effectively. It includes 120 adults with advanced or hard-to-remove pancreatic cancer who are already scheduled for standard chemotherapy…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Flemming Forsberg • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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New hope for pancreatic cancer: drug combo shows promise in early trial
Disease control OngoingThis study tests a new drug called mitazalimab combined with standard chemotherapy in people with metastatic pancreatic cancer that has spread. The goal is to see if the combination is safe and shrinks tumors. About 94 adults who have not had prior chemotherapy for this cancer wi…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Alligator Bioscience AB • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Can digestive enzymes help fight weight loss in pancreatic cancer?
Disease control OngoingThis study tests whether a pancreatic enzyme replacement called pancrelipase can help maintain or improve body weight in people with metastatic pancreatic cancer. About 17 participants will receive either the enzyme or a placebo, and researchers will measure changes in body mass …
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 06, 2026 16:15 UTC
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New immune cell therapy targets five Hard-to-Treat cancers
Disease control TerminatedThis early-stage trial was designed to test the safety of a new treatment called STIL101 for people with advanced pancreatic, colorectal, kidney, cervical cancer, or melanoma that has spread or cannot be removed. The treatment uses a patient's own immune cells (T cells) taken fro…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 05, 2026 11:53 UTC
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Antibiotic added to chemo in fight against tough pancreatic cancer
Disease control OngoingThis small, early-stage study is testing if adding a common antibiotic called ciprofloxacin to standard chemotherapy can help control advanced pancreatic cancer that has spread. It involves 10 patients who are new to treatment. The goal is to see if this combination is safe and i…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: National University Hospital, Singapore • Aim: Disease control
Last updated Apr 13, 2026 20:17 UTC
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New imaging tactic for Hard-to-Find cancers hits snag
Diagnosis TerminatedThis study aimed to test a new two-step PET imaging method to locate cancer cells that make a protein called CA19-9. It was designed for people with pancreatic, bladder, or gastrointestinal cancers. However, the study was withdrawn before enrolling any participants, so no results…
Matched conditions: METASTATIC PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Diagnosis
Last updated May 04, 2026 16:17 UTC