New Four-Drug attack on deadly pancreatic cancer enters human testing

NCT ID NCT05669482

Summary

This study is testing a new combination of four drugs for people with metastatic pancreatic cancer who have not yet received any treatment. The main goals are to find the safest and most effective dose of the new drug pair (avutometinib and defactinib) when added to two standard chemotherapy drugs. Researchers will measure how well the tumors shrink and how long patients live without their cancer getting worse.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Fred Hutchinson Cancer Center

    Seattle, Washington, 98109, United States

  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health

    New York, New York, 10016, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • New York Presbyterian/Weill-Cornell Medical Center

    New York, New York, 10021, United States

  • UCSF Helen Diller Family Comprehensive Cancer Center

    San Francisco, California, 94158, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Michigan Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Utah Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.