METASTATIC COLORECTAL CARCINOMA
Clinical trials for METASTATIC COLORECTAL CARCINOMA explained in plain language.
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Early trial tests new drug combo for Tough-to-Treat cancers
Disease control OngoingThis early-stage study aims to find the safest and most effective dose of a new drug, M6620, when given with the chemotherapy drug irinotecan. It is for adults with advanced solid tumors, like certain colorectal, pancreatic, or lung cancers, that have spread or cannot be removed …
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Personalized immune cells tested to fight five tough cancers
Disease control TerminatedThis early-stage study aimed to test the safety and early effectiveness of a personalized cell therapy called STIL101. The therapy involved growing a patient's own cancer-fighting immune cells (T-cells) from a tumor sample in a lab and then infusing them back. It was designed for…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Zapping lung cancer: heat vs. scalpel in Head-to-Head trial
Disease control OngoingThis study is comparing two standard ways to treat small lung tumors: a minimally invasive procedure that uses microwave energy to heat and destroy the tumor, and a small surgery to cut it out. Researchers want to see which method is safer, more effective at keeping the cancer fr…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New hope for Tough-to-Treat colon cancer patients
Disease control OngoingThis early-stage trial is testing whether combining existing cancer drugs with a new experimental drug (LY3214996) can help control advanced colorectal cancer that has stopped responding to standard treatments. The study aims to find safe doses and see if these combinations can s…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Double-Duty treatment: can radiation boost cancer immunotherapy?
Disease control OngoingThis study is testing whether adding radiation therapy to two immunotherapy drugs helps control advanced lung and colorectal cancer better than the drugs alone. It enrolled 110 patients whose cancer had spread and had stopped responding to prior treatments. The main goals are to …
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New Two-Drug attack on Tough-to-Treat colon cancer
Disease control OngoingThis study is testing a new two-drug combination for people with advanced colorectal cancer that has spread and is no longer responding to standard chemotherapy. The trial combines an experimental pill called SX-682, which aims to block tumor growth, with an existing immunotherap…
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Scientists test new Cancer-Fighting duo in early trial
Disease control OngoingThis early-stage study is testing a new combination of two existing cancer drugs, pembrolizumab and ziv-aflibercept, in patients with advanced solid tumors. The main goal is to find the safest and most effective dose of the combination. Researchers will also look for early signs …
Matched conditions: METASTATIC COLORECTAL CARCINOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC