MELASMA
Clinical trials for MELASMA explained in plain language.
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New hope for melasma: common diabetes drug may lighten dark patches
Disease control Not yet recruitingThis study tests whether a metformin cream or a tranexamic acid cream works better for treating melasma, a skin condition causing dark patches on the face. About 70 adults with melasma will apply one of the creams daily for 12 weeks. Doctors will measure changes in the size and d…
Matched conditions: MELASMA
Phase: NA • Sponsor: Foundation University Islamabad • Aim: Disease control
Last updated May 04, 2026 16:24 UTC
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Could a diabetes drug beat a standard melasma treatment?
Symptom relief Not yet recruitingThis study tests whether a cream made from 30% metformin (a diabetes drug) works better and causes fewer side effects than the standard Kligman's regimen for treating melasma, a skin condition causing dark patches on the face. About 82 women aged 35-55 will use one of the two cre…
Matched conditions: MELASMA
Phase: NA • Sponsor: Foundation University Islamabad • Aim: Symptom relief
Last updated May 09, 2026 05:19 UTC
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New combo therapy for melasma shows promise in early trial
Symptom relief Not yet recruitingThis study tests whether taking an oral medication (tranexamic acid) along with a skin treatment (microneedling with glutathione) works better than either treatment alone for melasma, a condition causing dark patches on the face. The trial will involve 42 women aged 18 to 50 with…
Matched conditions: MELASMA
Phase: PHASE2, PHASE3 • Sponsor: Assiut University • Aim: Symptom relief
Last updated May 07, 2026 18:42 UTC
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New gel aims to lighten melasma with fewer side effects
Symptom relief Not yet recruitingThis study tests a new gel for melasma, a skin condition causing dark patches on the face. The gel combines tranexamic acid, aloe, and a penetration enhancer to improve effectiveness and reduce side effects. Ten women with melasma will apply the gel for 12 weeks, and doctors will…
Matched conditions: MELASMA
Phase: NA • Sponsor: The First Affiliated Hospital of Xinxiang Medical College • Aim: Symptom relief
Last updated May 05, 2026 11:57 UTC
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Cream showdown: which fades melasma better?
Symptom relief Not yet recruitingThis study compares two creams—tranexamic acid and ethyl ascorbic acid—to see which works better for melasma, a condition causing dark patches on the skin. About 128 adults aged 18 to 50 with melasma will apply one of the creams and be monitored for improvement. The goal is to fi…
Matched conditions: MELASMA
Phase: PHASE4 • Sponsor: Hayatabad Medical Complex • Aim: Symptom relief
Last updated May 04, 2026 16:21 UTC