MELASMA
Clinical trials for MELASMA explained in plain language.
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Skin needles beat pills for melasma? new study shows promise
Disease control CompletedThis study tested whether injecting tranexamic acid directly into the skin works better than taking it as a pill for melasma, a common skin condition causing dark patches. 218 adults with melasma took part. Researchers measured changes in the Melasma Area and Severity Index after…
Matched conditions: MELASMA
Phase: EARLY_PHASE1 • Sponsor: Hayat Abad Medical Complex, Peshawar • Aim: Disease control
Last updated May 06, 2026 16:14 UTC
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Stem cell exosomes plus laser shows promise for stubborn melasma
Disease control CompletedThis study tested a new treatment for melasma, a stubborn skin condition causing dark patches on the face. Researchers combined umbilical cord stem cell exosomes with a non-ablative fractional laser in 30 adults aged 18 to 60. The goal was to see if this combination could reduce …
Matched conditions: MELASMA
Phase: NA • Sponsor: Fujian Medical University Union Hospital • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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New gel vs standard cream: which fades melasma better?
Symptom relief CompletedThis study tested two creams for melasma, a skin condition causing dark patches on the face. 34 adults used either a triple combination cream or a metformin gel every night for 12 weeks, plus sunscreen during the day. Researchers measured how much the dark spots improved to see w…
Matched conditions: MELASMA
Phase: NA • Sponsor: Jinnah Postgraduate Medical Centre • Aim: Symptom relief
Last updated May 09, 2026 05:21 UTC
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Cream showdown: which fades dark spots better?
Symptom relief CompletedThis study tested two creams—20% azelaic acid and 4% hydroquinone—on 146 adults with melasma, a condition causing dark patches on the face. Participants applied the cream daily for 12 weeks, and doctors checked how much the patches faded each month. The goal was to see which crea…
Matched conditions: MELASMA
Phase: NA • Sponsor: Gujranwala medical college District Headquarters Hospital, Gujranwala • Aim: Symptom relief
Last updated May 06, 2026 16:03 UTC
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New needle treatment may fade melasma in darker skin
Symptom relief CompletedThis study tested whether radiofrequency microneedling (RFMN) can safely treat melasma, a condition causing dark patches on the face, in people with darker skin (Fitzpatrick types IV-VI). Ten adults completed the treatment, and researchers measured changes in melasma severity usi…
Matched conditions: MELASMA
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Screen light fears overblown? melasma study finds no major impact
Knowledge-focused CompletedThis study looked at whether blue light from computer or TV screens makes melasma (a skin condition causing dark patches on the face) worse. Twelve women with melasma had one side of their face exposed to simulated screen blue light for 5 days, while the other side was not expose…
Matched conditions: MELASMA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated May 08, 2026 12:01 UTC