MELASMA
Clinical trials for MELASMA explained in plain language.
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Injection or pill? new study tests better melasma fix
Disease control CompletedThis study tested whether injecting tranexamic acid into the skin works better than taking it as a pill for melasma, a common skin condition causing dark patches. 218 adults with melasma took part. Researchers measured how much the skin improved after 8 weeks using a standard sco…
Matched conditions: MELASMA
Phase: EARLY_PHASE1 • Sponsor: Hayat Abad Medical Complex, Peshawar • Aim: Disease control
Last updated Jun 22, 2026 12:06 UTC
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Stem cell exosomes plus laser shows promise for stubborn melasma
Disease control CompletedThis study tested a new treatment for melasma, a stubborn skin condition causing dark patches on the face. Researchers combined stem cell exosomes (tiny particles from umbilical cord cells) with a special laser in 30 adults. The goal was to see if this combo is safe and works bet…
Matched conditions: MELASMA
Phase: NA • Sponsor: Fujian Medical University Union Hospital • Aim: Disease control
Last updated Jun 22, 2026 12:02 UTC
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Cream showdown: which works better for dark spots?
Disease control CompletedThis study tested two creams—20% azelaic acid and 4% hydroquinone—on 146 adults with melasma, a condition causing dark patches on the face. Participants applied the cream daily for 12 weeks, and doctors tracked changes in patch size and color. The goal was to see which cream work…
Matched conditions: MELASMA
Phase: NA • Sponsor: Gujranwala medical college District Headquarters Hospital, Gujranwala • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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New needle treatment may fade melasma in darker skin
Disease control CompletedThis study tested whether radiofrequency microneedling can safely treat melasma in people with darker skin tones (Fitzpatrick types IV-VI). Ten adults with melasma received the treatment, and doctors measured changes in severity using a standard scoring system. The goal was to se…
Matched conditions: MELASMA
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 12, 2026 12:04 UTC
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Could a diabetes drug gel fade melasma? small study pits metformin against standard cream
Symptom relief CompletedThis study tested whether a 30% metformin gel applied nightly can reduce melasma (dark patches on the face) as well as a standard triple cream containing hydroquinone, tretinoin, and a steroid. Thirty-four adults with melasma used one of the two treatments plus sunscreen for 12 w…
Matched conditions: MELASMA
Phase: NA • Sponsor: Jinnah Postgraduate Medical Centre • Aim: Symptom relief
Last updated Jun 24, 2026 12:03 UTC
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Can new serums outshine hydroquinone for melasma?
Symptom relief CompletedThis 4-week pilot study tested two brightening serums against 4% hydroquinone in 18 adults with hyperpigmentation or melasma. Each participant used different products on each side of their face to compare results. The goal was to see if the serums could improve skin tone evenness…
Matched conditions: MELASMA
Phase: NA • Sponsor: Revision Skincare • Aim: Symptom relief
Last updated Jun 24, 2026 12:01 UTC
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Screen time and skin spots: new study investigates blue Light's effect on melasma
Knowledge-focused CompletedThis study looked at whether blue light from computer and TV screens can make melasma (a common skin condition causing dark patches on the face) worse. Twelve women with melasma had one side of their face exposed to blue light for 30 minutes a day over 5 days, while the other sid…
Matched conditions: MELASMA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:53 UTC