New hope for melasma: common diabetes drug may lighten dark patches

NCT ID NCT07495748

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a metformin cream or a tranexamic acid cream works better for treating melasma, a skin condition causing dark patches on the face. Seventy adults with melasma will apply one of the creams daily for 12 weeks, along with sunscreen. The main goal is to see which cream reduces the size and darkness of the patches more effectively.

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Conditions

The condition(s) this trial relates to.

Melanosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fauji Foundation Hospital, Rawalpindi

    Rawalpindi, Punjab Province, 44000, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact