Skin pigment battle: which melasma treatment wins?

NCT ID NCT07604844

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two treatments for melasma, a skin condition causing dark patches on the face. One group gets injections of tranexamic acid, the other gets mandelic acid chemical peels. Researchers will track pigmentation improvement and quality of life in 120 adults over several sessions.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
tranexamic acid and mandelic acid
What this could lead to
If successful, this study could show which treatment is more effective for reducing melasma pigmentation in South Asian skin types.
What could go wrong
This is a small, early-stage trial with no phase designation, so results may not apply broadly. Both treatments are cosmetic and not a cure.

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Conditions

The condition(s) this trial relates to.

Hyperpigmentation Melanosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Combined Military Hospital, Abbottabad

    Abbottabad, KPK, 22010, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.