Skin pigment battle: which melasma treatment wins?

NCT ID NCT07604844

First seen May 29, 2026

Summary

This study compares two treatments for melasma, a skin condition causing dark patches on the face. One group gets injections of tranexamic acid, the other gets mandelic acid chemical peels. Researchers will track pigmentation improvement and quality of life in 120 adults over several sessions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Combined Military Hospital, Abbottabad

    Abbottabad, KPK, 22010, Pakistan

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tranexamic acid and mandelic acid

What this could lead to

If successful, this study could show which treatment is more effective for reducing melasma pigmentation in South Asian skin types.

What could go wrong

This is a small, early-stage trial with no phase designation, so results may not apply broadly. Both treatments are cosmetic and not a cure.

Conditions

The condition(s) this trial relates to.

Hyperpigmentation Melanosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.