MALOCCLUSION
Clinical trials for MALOCCLUSION explained in plain language.
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New study compares three aligner designs for perfect smiles
Disease control Recruiting nowThis study tests SureSmile clear aligners in 90 adults with crooked teeth (malocclusion). It compares three different aligner edge designs to see which moves teeth most accurately. Participants wear the aligners as usual, and researchers measure tooth movement against predictions…
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: Dentsply Sirona Implants and Consumables • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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AI-Powered smiles: could smart monitoring shorten braces time?
Disease control Recruiting nowThis study tests whether artificial intelligence and remote monitoring can help orthodontists decide when to switch to the next set of clear aligners, instead of using a fixed schedule. Participants wear clear aligners and use a smartphone app that tracks tooth movement with AI. …
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: University of Illinois at Chicago • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Digital smile makeover: new trial uses face scans to guide Full-Mouth rehab
Disease control Recruiting nowThis study tests a fully digital method for full-mouth dental rehabilitation in 10 adults aged 20-45 with bite problems, missing teeth, or smile concerns. The approach uses 3D scans of the teeth, face, and jaw to plan treatment, which may include tooth movement, guided implant pl…
Matched conditions: MALOCCLUSION
Sponsor: Menoufia University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Clear aligners take on braces in overbite showdown
Disease control Recruiting nowThis study tests whether clear aligners with rubber bands can correct a mild overbite (Class II malocclusion) as well as traditional braces. Twenty-four people aged 15-20 will be randomly assigned to either clear aligners or braces, both with elastics. Researchers will measure ch…
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: Hama University • Aim: Disease control
Last updated Jun 26, 2026 16:59 UTC
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Which clear aligner design feels better? new study aims to find out
Symptom relief Recruiting nowThis study compares two common clear aligner trimming-line designs to see which one feels more comfortable to wear. Seventy orthodontic patients who already wear one design on their upper teeth and the other on their lower teeth will rate their comfort after at least four weeks. …
Matched conditions: MALOCCLUSION
Sponsor: George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures • Aim: Symptom relief
Last updated Jul 08, 2026 00:00 UTC
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Pineapple enzyme may reduce Post-Surgery swelling
Symptom relief Recruiting nowThis study tests whether a bromelain supplement (an enzyme from pineapple) can reduce facial swelling after jaw surgery. About 200 people having jaw surgery will take the supplement for 9 days (starting 2 days before surgery). Researchers will use 3D imaging to measure swelling a…
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: Mohamed Bazina • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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Braces breakthrough? tiny wire tied to less pain and fewer problems
Symptom relief Recruiting nowThis study looks at a small wire called a laceback used with braces. It checks if the laceback affects how clean teeth stay, how often wires break, and how much pain people feel. About 38 people getting braces will have one side of their mouth get the laceback and the other side …
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: International Islamic University Malaysia • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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Clear plastic expander could replace metal jaw widener for teens
Symptom relief Recruiting nowThis study compares a new clear plastic expander to the standard metal Hyrax expander for widening the upper jaw in 40 teens aged 10-14 with narrow jaws. The goal is to see if the clear device works as well for correcting crossbites and improving jaw width. Participants will be r…
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: University of Baghdad • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New braces system promises quicker smiles with less pain
Symptom relief Recruiting nowThis study tests a new orthodontic system called I-arch to see if it straightens moderately crooked teeth faster and with less discomfort than standard braces. About 34 people aged 12 and older with mild to moderate crowding will take part. Researchers will measure alignment spee…
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: Tabark H. Omran • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Jaw surgery may lift depression along with the bite
Knowledge-focused Recruiting nowThis study looks at whether corrective jaw surgery (orthognathic surgery) can improve depressive symptoms and how patients see their own appearance. Researchers will compare questionnaire results from before and six months after surgery in 20 adults with different types of malocc…
Matched conditions: MALOCCLUSION
Sponsor: Kırıkkale University • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Digital braces bonding could cut chair time for teens
Knowledge-focused Recruiting nowThis study compares two ways of attaching braces: a digital method using computer planning versus the traditional manual approach. Twenty teenagers needing braces on both upper and lower teeth will receive one method on the top and the other on the bottom. Researchers will measur…
Matched conditions: MALOCCLUSION
Phase: NA • Sponsor: Azienda Ospedaliero-Universitaria Careggi • Aim: Knowledge-focused
Last updated Jul 11, 2026 00:00 UTC
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Jaw surgery may fix more than your Smile—Could it improve speech?
Knowledge-focused Recruiting nowThis study looks at how jaw surgery affects speech in people with bite problems like open bite or underbite. Researchers will record patients' speech and tongue movements before and after surgery to see what changes. The goal is to understand why many jaw surgery patients have sp…
Matched conditions: MALOCCLUSION
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC
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Jaw muscle changes seen in kids with enlarged adenoids – new study
Knowledge-focused Recruiting nowThis observational study uses ultrasound to compare the jaw (masseter) muscle in children aged 3 to 8 with and without enlarged adenoids. Researchers will measure muscle thickness and structure, and check dental bite patterns. The goal is to see if adenoid hypertrophy is linked t…
Matched conditions: MALOCCLUSION
Sponsor: Melis AKYILDIZ • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC