MALIGNANT NEOPLASM

This study is testing a two-part treatment for advanced cancer. Doctors take a patient's own white blood cells, genetically modify them to recognize a specific cancer protein (NY-ESO-1), and infuse them back. This is combined with a vaccine made from the same protein to boost the…

This early-stage trial aims to find safe doses and understand side effects of several drug combinations for patients with advanced cancers that haven't responded to standard treatments. The study involves 155 participants with various advanced or metastatic cancers and some rare …

This study is testing whether a non-invasive brain stimulation technique can reduce nerve pain caused by a common chemotherapy drug. Researchers are comparing real magnetic stimulation to a fake (placebo) treatment and standard care in 56 cancer patients. The goal is to see if st…

This study is testing whether a common steroid drug called dexamethasone can help control severe shortness of breath in cancer patients. About 135 participants with cancer and significant breathlessness were randomly assigned to receive either the drug or a placebo for two weeks.…

This study is testing whether using virtual reality (VR) headsets during painful cancer procedures can help reduce patients' pain and anxiety. Hospitalized cancer patients undergoing bone marrow biopsies or lumbar punctures will either use VR during the procedure or receive stand…

This study tested whether cancer patients could use a simple meditation app on their own to help manage feelings of anxiety and depression. Researchers enrolled 35 patients at MD Anderson Cancer Center who reported significant distress. Participants either used the meditation app…

This study aims to understand how cancer treatment affects children's muscle mass, physical strength, and aging markers. Researchers will measure 28 children ages 8-21 at diagnosis, during treatment, and after treatment using simple tests and routine scans. The goal is to learn h…

This study aims to understand why some cancer patients have remarkable, unexpected recoveries from treatments that fail for most others. Researchers will analyze tumor samples from about 170 of these 'exceptional responders' to look for unique genetic patterns. The goal is to dis…

This study is testing a secure website designed to help families with a known inherited cancer risk. The program helps the person who had genetic testing share their results and relevant health history with their at-risk relatives. The goal is to improve communication within fami…