MALIGNANT NEOPLASM

This early-phase study tested a new experimental drug called HMBD-002, alone or with another cancer drug (pembrolizumab), in 48 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see …

This early-phase study tested a new drug called MK-4700, given alone or with another cancer drug (pembrolizumab), in 5 people with advanced solid tumors that had stopped responding to other treatments. The main goal was to check safety and find a dose that people can tolerate. No…

This study tested a team-based care program for 516 people with stage III or IV cancer. The program aimed to help them stay mobile, reduce pain, and improve quality of life. Researchers found that the program helped maintain physical function and eased pain over six months.

This study tested whether one or two doses of radiation therapy works better to reduce pain in cancer patients whose disease has spread to the bones. A total of 102 adults with painful bone metastases received either a single dose or two doses of radiation. The goal was to see if…

This study looked at whether ringing a bell on the last day of radiation therapy helps cancer patients remember their treatment as less painful or distressing. 82 cancer patients were involved, and researchers compared their memories of distress between those who rang a bell and …

This study tested whether taking extra dietary fiber (from psyllium husk capsules) during pelvic radiation therapy can reduce long-term gut inflammation and side effects in cancer patients. 354 adults with cancers of the pelvis (like rectal, prostate, or gynecological cancers) we…

This study tested a short-term psychodynamic therapy for 24 adults with advanced solid tumors and high psychological distress. The goal was to see if the therapy was safe, acceptable, and feasible, not to cure the cancer. Results focused on side effects, drop-out rates, and patie…

This study tested whether using a virtual reality headset during a single chemotherapy session could help cancer patients feel less distressed, anxious, or in pain. 68 adults with any type of cancer and high distress levels were randomly assigned to either use virtual reality for…

This study tested whether ketoconazole, a drug usually used for fungal infections, can help reduce skin rashes caused by EGFR inhibitor cancer therapy. 58 participants with ongoing rash were randomly assigned to receive ketoconazole or a placebo. The main goal was to see if the d…

This study looked at whether using at-home monitoring devices (like a wristband pedometer, scale, and blood pressure cuff) can help improve care for cancer patients after they leave the hospital following surgery. 22 people with different cancers took part. The goal was to see if…

This study looked at whether it's possible to repeatedly measure muscle mass, physical function, and biological aging in children (ages 8-21) with newly diagnosed solid tumors or lymphoma during cancer treatment. Researchers used simple tests like walking and grip strength, along…