Timing of brain radiation may improve cancer control

NCT ID NCT03741673

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This phase III trial tests whether giving focused radiation before surgery for brain metastases works better than giving it after surgery. The study involves 180 patients with cancer that has spread to the brain. Researchers will compare how well each approach controls the disease and reduces the chance of cancer spreading in the brain lining.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

stereotactic radiosurgery (focused radiation)

What this could lead to

If it works, this could establish the best timing for radiation to control brain metastases and reduce the risk of cancer spreading in the brain lining.

What could go wrong

This is a phase III trial, but results may not apply to all patients. The study is still recruiting, and the outcomes are about disease control, not a cure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

brain cancer cancer metastatic malignant neoplasm in the brain neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-••••

    Contact