MALIGNANT BRAIN NEOPLASM

This study is testing if patient care for brain tumor survivors can be done remotely using online tests and a smartwatch. It also compares whether adding the diabetes drug metformin helps protect memory and thinking skills that can decline after head radiation. About 100 adults w…

This is a first-in-human safety study for children whose aggressive brain tumors have come back or stopped responding to standard treatments. Doctors are testing a new type of treatment where a child's own immune cells are collected, genetically reprogrammed in a lab to hunt for …

This study is testing two new types of MRI scans to see if they can better tell the difference between a brain tumor that has grown back and harmless scar tissue caused by past radiation treatment. Currently, standard scans often look the same, making it hard for doctors to decid…

This study is testing a special fluorescent dye attached to an antibody (panitumumab-IRDye800) that sticks to brain tumor cells. During surgery, a special camera can see the glowing dye, which may help surgeons better tell tumor tissue apart from healthy brain tissue and find sma…

This study is testing if a shorter, lower dose of steroids (dexamethasone) after brain tumor surgery can reduce side effects like high blood sugar and poor wound healing, without increasing the risk of dangerous brain swelling. It will compare a 4-day steroid schedule to the stan…

This study is testing whether a daily routine of guided breathing exercises can improve brain health and mental well-being. It is enrolling patients with multiple sclerosis or certain cancers, as well as their caregivers, to see if the practice reduces symptoms like fatigue, anxi…

This study aims to understand how personal relationships and physical activity affect the well-being of young adults who have survived cancer. Researchers will follow 250 young adult survivors for one year, having them complete surveys and wear activity trackers. The goal is to l…

This study aims to learn more about the tiny blood vessels that feed solid tumors. Researchers will use a special microscope during a patient's standard cancer surgery to see these vessels in real time. The goal is to understand how tumor blood flow works and if it relates to how…

This early-phase study is testing whether a new radioactive tracer, called Zr-89 crefmirlimab berdoxam, can help doctors see immune cells inside brain tumors using a PET scan. The goal is to see if this non-invasive scan can accurately show where immune cells are active, which co…

This study aims to understand how cancer-related genetic mutations differ among various ethnic populations. Researchers will collect blood or saliva samples from 1,800 cancer patients from diverse backgrounds to identify genetic patterns. The findings could help create more perso…

This study is testing whether educational videos and guided appointments help young adults (ages 18-39) with advanced cancer have better conversations about their future medical care preferences. Researchers want to see if these tools make it easier for patients to discuss and do…