MALARIA

This study tests a shorter, higher-dose treatment for vivax malaria to prevent it from coming back. Current treatments take too long, but a 3-day course may be just as safe and effective. About 1,019 people with malaria will take part to see if this ultra-short course works bette…

This study tests whether a new drug combination (SJ733 plus tafenoquine) can cure P. vivax malaria in adults. P. vivax malaria can come back months after treatment, so the goal is a 'radical cure' that clears the parasite completely. About 104 participants will receive the drugs …

This study tests whether a half-dose of the R21/Matrix-M malaria vaccine works as well as the full dose in 375 adults and adolescents aged 14 to 60. Participants will receive either the standard dose or one of two half-dose versions. The goal is to see if using less vaccine can s…

This early-stage study tests a single injection of MMV371, a long-acting medicine, to see if it safely prevents malaria in healthy adults and teens aged 12-50 in Rwanda. About 80 participants will get either the study drug or a placebo, and researchers will monitor them for 24 we…

This study tests whether giving malaria medicine to school-age children can lower malaria cases in the entire community. Since children often carry the parasite without symptoms, treating them may stop the spread to others. The trial will involve about 4,800 students in The Gambi…

This study will test whether new LASER Guardian devices that release mosquito-repelling chemicals can help prevent malaria in Kenyan communities. Researchers will compare these devices against standard indoor insecticide spraying and current prevention methods across 69 villages …

This study looks at how three malaria drugs (piperaquine, pyronaridine, and artesunate) interact when taken together. It involves 24 healthy adults in Thailand who will receive the drugs in different orders and be monitored for side effects and drug levels. The goal is to underst…