MALARIA

This large, final-stage trial is testing whether a new vaccine called R21/Matrix-M can safely protect young children in Africa from getting sick with malaria. It involves 4,800 children aged 5-36 months across several African countries. The study compares the malaria vaccine agai…

This is an early-stage study to check if a new experimental malaria vaccine is safe and can trigger an immune response. It will involve 22 healthy adults who have never had malaria. Researchers will give participants the vaccine or a placebo, then later expose them to malaria par…

This study is testing a one-time antibody injection (L9LS) to see if it is safe for infants and if it interferes with a later malaria vaccine. It involves 180 healthy infants in Mali, aged 1 to 12 months. Researchers will give some infants the antibody and others a placebo, then …

This study aims to test the safety of an experimental malaria vaccine (PfSPZ) in pregnant women. It involves 400 healthy pregnant participants in Mali who will receive either the vaccine or a placebo injection. Researchers will closely monitor the women and their babies for over …

This study is testing two new types of insecticide-treated mosquito nets to see if they are better than standard nets at preventing malaria in children and communities. The trial involves 1,650 people across 33 villages in central Côte d'Ivoire, an area with high malaria rates an…

This study aims to gather detailed information about how often people in two Liberian villages get malaria over time. Researchers will follow about 400 residents of all ages for up to 3 years, checking them monthly for malaria infections and collecting mosquitoes from their homes…