Malaria vaccine trial for pregnant women launches in mali
NCT ID NCT05652504
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 3 times
Summary
This Phase 1 trial in Mali will test the safety of the PfSPZ malaria vaccine in 400 healthy pregnant women aged 18-34. Participants will receive three injections of either the vaccine or a placebo. The study will monitor both mothers and their infants for up to a year after birth to check for any harmful effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PfSPZ vaccine (radiation-attenuated malaria sporozoites)
What this could lead to
If successful, this could show that the PfSPZ vaccine is safe for pregnant women, potentially leading to a way to protect them and their babies from malaria.
What could go wrong
This is an early Phase 1 safety trial, so it is not designed to prove the vaccine works. The study is currently suspended, and results may not show a clear safety benefit or may reveal unexpected risks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ou(SqrRoot)(Copyright)less(SqrRoot)(Copyright)bougou, Health Research Center
Ou(SqrRoot)(Copyright)less(SqrRoot)(Copyright)bougou, Mali