LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Clinical trials for LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA explained in plain language.
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Experimental combo therapy targets Hard-to-Treat pancreatic cancer
Disease control Recruiting nowThis early-stage trial tests whether injecting an immune-boosting drug (mitazalimab) directly into the tumor during a special electrical ablation procedure (IRE) is safe for people with locally advanced pancreatic cancer. The goal is to see if this approach can strengthen the bod…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New drug cocktail aims to tackle tough pancreatic cancer
Disease control Recruiting nowThis study tests whether adding two new drugs (zimberelimab and quemliclustat) to standard chemotherapy can help shrink pancreatic tumors that are either borderline removable or have spread locally. About 56 adults with untreated pancreatic cancer will receive the combination. Th…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New chemo cocktail aims to shrink pancreatic tumors
Disease control Recruiting nowThis study compares two chemotherapy regimens for people with advanced pancreatic cancer that has spread or cannot be removed by surgery. One group gets NALIRIFOX (a mix of four drugs) every two weeks, while the other gets a modified version of gemcitabine, nab-paclitaxel, and ci…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New combo therapy aims to boost radiation for tough pancreatic tumors
Disease control Recruiting nowThis early-phase trial tests a drug called XER-001 (a form of amifostine given through a tube into the small intestine) combined with precise radiation therapy for people with locally advanced pancreatic cancer that cannot be removed by surgery. The study will enroll 36 participa…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Xerient Pharma • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Pulsed proton beams aim to tame tough pancreatic tumors
Disease control Recruiting nowThis phase II trial tests a new radiation technique called PULSAR, which delivers short, powerful proton beam pulses every few weeks, adapted to tumor changes. It is for people with locally advanced or limited metastatic pancreatic cancer who have already had some chemotherapy. T…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: PHASE2 • Sponsor: Samsung Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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New MRI scan could predict pancreatic cancer treatment success
Diagnosis Recruiting nowThis study tests an experimental MRI scan that uses a special contrast agent called hyperpolarized carbon-13 pyruvate to see how pancreatic tumors process nutrients. The goal is to find out if this scan can predict treatment response better than standard MRIs. About 70 adults wit…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Sponsor: University of California, San Francisco • Aim: Diagnosis
Last updated Jun 27, 2026 07:57 UTC
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New drug OMO-103 tested in early pancreatic cancer trial
Knowledge-focused Recruiting nowThis early phase 1 trial is studying how the drug OMO-103 affects pancreatic cancer cells in 12 patients with advanced or metastatic pancreatic ductal adenocarcinoma. The main goal is to see if the drug changes the tumor's biology by analyzing tissue samples before and after trea…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Pancreatic cancer drugs put to the test in early trial
Knowledge-focused Recruiting nowThis early phase trial is testing several targeted drugs in people with pancreatic cancer to see how they affect tumor biology. Researchers will compare tumor samples taken before and after treatment to understand which drugs might work best. The goal is not to treat the cancer d…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Genetic blueprint may unlock better pancreatic cancer care
Knowledge-focused Recruiting nowThis study looks at whether genetic information from tumors can help doctors choose better treatments for pancreatic cancer. About 200 adults with early or locally advanced pancreatic cancer will receive standard chemotherapy and provide blood, tissue, and fluid samples for genet…
Matched conditions: LOCALLY ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA
Phase: NA • Sponsor: British Columbia Cancer Agency • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC