LEPTOMENINGEAL DISEASE
Clinical trials for LEPTOMENINGEAL DISEASE explained in plain language.
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New chemo approach tested for aggressive breast cancer brain spread
Disease control Recruiting nowThis study tests whether high-dose methotrexate chemotherapy given through an IV can help patients with advanced breast cancer that has spread to the membranes surrounding the brain and spinal cord. Researchers want to see if this treatment helps patients live longer than 12 week…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Spinal fluid drug delivery offers hope for devastating brain cancer spread
Disease control Recruiting nowThis study is testing whether radiation therapy followed by targeted cancer drugs delivered directly into the spinal fluid is safe and effective for treating HER2-positive breast cancer that has spread to the lining of the brain and spinal cord. The trial will involve 39 patients…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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New Triple-Threat attack on breast Cancer's most devastating spread
Disease control Recruiting nowThis study is testing a combination of three drugs to treat a serious complication where HER2-positive breast cancer spreads to the fluid-filled lining around the brain and spinal cord. It aims to see if this approach can help patients live longer and improve their neurological s…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: UNICANCER • Aim: Disease control
Last updated Mar 20, 2026 14:47 UTC
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Doctors test First-Ever spinal fluid vaccine for deadly breast cancer brain spread
Disease control Recruiting nowThis is a first-in-human safety study testing a new immune-boosting vaccine for breast cancer that has spread to the membranes surrounding the brain and spinal cord. Researchers will give the vaccine directly into the spinal fluid of up to 18 patients to find the highest dose tha…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC