New hope for brain metastases: High-Dose chemo targets lethal spread
NCT ID NCT02422641
First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 29 times
Summary
This study tests a high dose of the chemotherapy drug methotrexate given through a vein in 16 adults with aggressive breast cancer that has spread to the lining of the brain. The goal is to see if this treatment can help people live longer than 12 weeks. Participants must have a specific type of breast cancer and be in good overall health.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Comprehensive Cancer Center at Wake Forest University (CCCWFU)
RECRUITINGWinston-Salem, North Carolina, 27157, United States
Contact Email: •••••@•••••
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Sidney Kimmel Comprehensive Cancer Center
RECRUITINGBaltimore, Maryland, 21287, United States
Contact Email: •••••@•••••
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Siteman Cancer Center- Washington University School of Medicine in St. Louis
ACTIVE_NOT_RECRUITINGSt Louis, Missouri, 63130, United States
Conditions
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