LEPTOMENINGEAL DISEASE
Clinical trials for LEPTOMENINGEAL DISEASE explained in plain language.
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New combo therapy targets breast cancer in the brain and spine
Disease control OngoingThis study tests whether radiation therapy followed by injecting two targeted antibodies (trastuzumab and pertuzumab) directly into the spinal fluid is safe and improves survival for people with HER2+ breast cancer that has spread to the lining of the brain and spine. About 33 pa…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1, PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Experimental vaccine targets breast cancer cells in the brain
Disease control OngoingThis early-phase trial tests a dendritic cell vaccine given directly into the spinal fluid for people with breast cancer that has spread to the lining of the brain (leptomeningeal disease). The vaccine is designed to train the immune system to attack cancer cells. The main goal i…
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE1 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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New drug shows promise for brain tumors from breast and lung cancer
Disease control OngoingThis study tests a drug called QBS72S in 21 adults with breast or lung cancer that has spread to the brain. The drug is given once a month through an IV. The main goal is to see if it shrinks brain tumors. The trial is active but not recruiting new participants.
Matched conditions: LEPTOMENINGEAL DISEASE
Phase: PHASE2 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC