KNEE OSTEOARTHRISTIS

This study tests a program that combines AI-guided exercise with continuous glucose monitoring for people who have both knee osteoarthritis and obesity. The goal is to see if it improves blood sugar control, reduces pain, and lowers the need for knee replacement surgery. About 31…

This study tests whether a single injection of stem cells (MAG200) can reduce pain and improve daily function in people with knee osteoarthritis. About 573 adults aged 35–75 with moderate knee arthritis will receive either a low dose, high dose, or placebo shot. The goal is to se…

This study tests whether combining blood-flow-restricted exercise (using light weights with a cuff to limit blood flow) and pain education can reduce pain and improve movement in people with knee osteoarthritis. About 90 adults aged 40 and older with knee OA will take part. The g…

This study looks at whether adding a gentle nerve-stretching technique (femoral nerve mobilization) to standard physical therapy can reduce pain and improve daily function in people with knee osteoarthritis. Fifty adults aged 50 and older with mild to moderate knee arthritis will…

This study looks at whether adding tissue flossing (wrapping an elastic band around the knee) to standard exercises can better reduce pain, improve movement, and strengthen muscles in people with knee osteoarthritis. About 58 adults aged 40-70 with mild to moderate knee OA will b…

This study tests two types of leg exercises—closed chain and open chain—done with a blood flow restriction cuff on the thigh, to see which better reduces pain and improves movement in people with mild knee osteoarthritis. Forty adults aged 45-75 with grade 1 or 2 knee OA will be …

This study compares two blood flow restriction training methods—band tissue flossing and traditional cuff—to see which better reduces pain, improves movement, and strengthens muscles in people with knee osteoarthritis. About 46 adults aged 40-60 with mild to moderate knee OA will…

This study tests if a single injection of hyaluronic acid (a gel-like substance) into the knee can safely reduce pain and stiffness in adults with knee osteoarthritis. Researchers will review medical records of 133 people aged 40-70 who received this one-dose treatment. The goal …

This study will compare sensory-motor training (exercises that improve body awareness and balance) with resistance training (strengthening exercises) in 52 adults aged 40-60 with early-stage knee osteoarthritis. The goal is to see which approach better reduces pain, improves bala…

This study compares focused shockwave therapy to standard physical rehabilitation for reducing pain in people with mild to moderate knee osteoarthritis. About 60 adults with grade I-III knee OA will be randomly assigned to receive either shockwave therapy alone or standard rehab.…

This study tests whether a special knee and heel brace, combined with strength exercises that don't involve standing, can reduce pain and improve walking in people with knee osteoarthritis. Twenty adults with knee arthritis will be randomly assigned to either the new brace or a s…

This study compares two minimally invasive procedures to relieve long-term knee pain caused by osteoarthritis. About 50 adults aged 45 to 85 with severe knee pain will receive either radiofrequency ablation (using heat) or a neurolytic alcohol injection to block pain signals. Res…

This study looks at two different FDA-approved machines that create platelet-rich plasma (PRP) for people with knee osteoarthritis. PRP is made from your own blood and may help with joint pain. The researchers will check if the PRP from each machine has different amounts or types…