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New brace and exercise combo aims to ease knee arthritis pain

NCT ID NCT07562685

Symptom relief Sponsor: Lahore University of Biological and Applied Sciences Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special knee and heel brace, combined with strength exercises done while sitting or lying down, can reduce pain and improve walking in people with knee osteoarthritis. Twenty participants will be randomly assigned to get either this new brace or a standard knee brace, along with the same exercise program, for four weeks. Researchers will measure pain, walking patterns, and daily function before and after treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Knee and Heel Off-Loader Brace with Non-Weight Bearing Strength Training
What this could lead to
If it works, this could point toward a better way to reduce pain and improve walking for people with knee osteoarthritis without surgery.
What could go wrong
This is a very small pilot study with only 20 people over 4 weeks. Results may not apply to everyone, and the brace may not provide lasting relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

35 to 50 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinically diagnosed KOA with radiographic Kellgren and Lawrence grade II-III, confirmed within the previous six months * History of knee pain for at least three months, consistent with chronic KOA * Ability to ambulate independently, with or without assistive devices * No change in pharmacological management for KOA during the previous three months * Ability to understand instructions and complete self reported outcome measures * Willingness to participate and provision of written informed consent Exclusion Criteria: * Severe venous insufficiency or history of deep vein thrombosis * Acute inflammatory knee conditions (e.g., septic arthritis, acute synovitis) * Rheumatic or systemic inflammatory joint diseases (e.g., rheumatoid arthritis) * Traumatic onset of knee pain within the previous six months * History of major lower limb injury or surgery requiring rehabilitation within the past year * Neurological or neurodegenerative disorders affecting gait or balance, including Parkinson's disease

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee osteoarthristis

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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