KIDNEY DISEASES

This study tests whether teaching kidney transplant recipients to eat a whole-food plant-based diet can improve their blood pressure, blood sugar, and weight, and reduce hospital visits. About 49 adults who had a kidney transplant in the past year and have high blood pressure, hi…

This study tests a new drug called savolitinib against a standard treatment (sunitinib) for people with a rare, advanced kidney cancer called MET-driven papillary renal cell carcinoma. The goal is to see if savolitinib works better at slowing cancer growth and has fewer side effe…

This study looks at whether raising the magnesium level in the fluid used during dialysis can help people with end-stage kidney disease live longer and avoid heart-related hospital stays. Many dialysis patients have low magnesium, which is linked to higher risks of death, heart i…

This study aimed to see if a special blood filter (Seraph 100) could reduce BK virus levels in kidney transplant patients with high viral loads. It planned to enroll adults with BK virus levels of 10,000 IU/mL or more who already had dialysis access. However, the study was withdr…

This study compares two drugs—methocarbamol and oxybutynin—to see which better reduces pain and discomfort from ureteral stents placed after kidney stone surgery. About 126 adults aged 18-80 who had ureteroscopy will take one of these medicines alongside standard pain relievers. …

This study follows about 3,000 adults in Port-au-Prince, Haiti, for up to 7 years to track heart disease risks like high blood pressure, diabetes, and smoking. Researchers will measure how common these risks are and how they lead to heart attacks, strokes, or heart failure. The g…

This study aims to understand why some people with diabetes develop kidney disease, focusing on social, environmental, and biological factors in Ecuador. Researchers will collect data from over 10,000 adults, including those with and without diabetes, to identify early signs and …

This study looks at why Black people with HIV are more likely to develop kidney disease, diabetes, and heart problems. Researchers are analyzing genetic and health data from over 3,000 participants to find risk factors. The goal is to better understand these diseases and improve …

This study compares two methods to help Hispanic/Latino and American Indian patients with kidney failure complete transplant evaluation and receive a kidney transplant. About 376 adults will be randomly assigned to either a streamlined evaluation process or a peer-assisted progra…

This study follows 600 people with and without chronic kidney disease (CKD) for up to 4 years to see how memory, thinking, and daily activities change over time. Researchers will compare the two groups and look for risk factors that may lead to cognitive decline, dementia, or str…

This study gathers medical images (MRI, CT, ultrasound) and related health data from 300 adults—both healthy volunteers and those with kidney or brain diseases. The goal is to create a secure collection that scientists can use for future not-for-profit research. No new treatments…

This study tests whether an educational program and mobile health tools can help adults with kidney failure find a living donor for a transplant. About 775 participants who haven't yet identified a donor will take part. The goal is to see if these tools increase the number of liv…

This study planned to test a technique that uses heat to seal the needle track after a liver, kidney, or spleen biopsy, aiming to reduce bleeding in patients at high risk. It was withdrawn before enrolling any participants. The goal was to see how well patients and doctors tolera…

This study tests whether a telehealth program, called a Living Donor Navigator, can help more people with kidney disease find living donors. About 347 patients will be randomly assigned to receive the navigator service right away or after a delay. The goal is to see if remote sup…