KIDNEY CANCER

This study aimed to see if adding the diabetes medication acarbose to standard immunotherapy is safe and tolerable for people with advanced kidney cancer that has spread. Researchers wanted to check if this combination could help control the cancer better and see how it affects t…

This study is testing whether using a patient's own blood during surgery for advanced kidney cancer can reduce the need for donor blood transfusions. Researchers are comparing standard blood management to techniques that collect and reuse the patient's blood during the operation.…

This study is testing a device that uses focused sound waves to destroy small kidney tumors without making any cuts. It enrolled 67 adults with single, small kidney tumors to see if the treatment safely eliminates the tumor tissue. Researchers will follow participants for five ye…

This study is testing if a robotic surgery for kidney cancer can be done without using stitches to close the wound. Instead, surgeons use controlled heat (cautery) to seal the area. Researchers want to see if this 'sutureless' method is just as safe and effective as the standard …

This early-stage trial is testing whether adding an experimental oral drug called AZD6244 to standard chemotherapy is safe for people with advanced cancers like breast, lung, colon, and kidney cancer. The study will find the highest dose patients can tolerate and track how the bo…

This early-stage study is testing the safety of a new, personalized vaccine designed to stop kidney cancer from returning after surgery. The vaccine is custom-made for each patient using unique markers from their own tumor. Researchers combine this vaccine with an approved immuno…

This study is testing whether a targeted radiation drug called 177Lu-PSMA-617 can help control advanced kidney cancer that has spread. The treatment works by seeking out cancer cells and delivering radiation directly to them. The trial involves about 24 patients whose cancer has …

This study aims to find the best order to give three existing kidney cancer drugs to patients whose cancer has spread. Researchers are testing six different two-drug sequences to see which order works best to control the disease and is safest. The trial involves 180 patients with…

This study is testing the safety and performance of Medtronic's new Hugo robotic surgery system for urologic procedures, primarily for cancers of the bladder, prostate, and kidney. It will enroll 144 adult patients needing specific cancer surgeries to see if the robot can complet…

This study planned to test a special gel called PuraBond that helps stop bleeding during kidney cancer surgery. The gel forms a protective barrier when applied to surgical wounds. The trial was withdrawn before any patients were enrolled, so no results are available.

This study is testing whether combining a targeted radiation drug (177Lu-girentuximab) with an immunotherapy drug (nivolumab) is safe and effective for treating advanced kidney cancer that has a specific protein (CAIX). It is for adults with clear cell kidney cancer that has spre…

This study is testing whether a 12-week support program can be successfully added to regular follow-up care for men living with advanced cancers of the prostate, kidney, bladder, testicles, or penis. The program includes nutrition advice, physical therapy, and other support servi…

This early-stage study is testing a tiny, implantable device to see if it can safely help doctors figure out which cancer drugs work best for an individual's kidney tumor. The device, placed into a tumor before surgery, releases tiny amounts of 19 different drugs already used to …

This study is testing a new system designed to give doctors a more complete picture of an older patient's overall health and life circumstances when planning cancer treatment. It combines questions about aging, daily function, mental health, and social needs like housing and food…

This study aims to determine if measuring two specific proteins (MMP2 and MMP9) in blood can help predict how well patients with metastatic kidney cancer will respond to anti-angiogenic drugs like Sunitinib or Pazopanib. Researchers will compare protein levels in 50 patients rece…