INTRACEREBRAL HEMORRHAGE

This study tests whether minocycline, an antibiotic, can improve recovery after a brain bleed (intracerebral hemorrhage). About 1,248 adults will receive either standard care or standard care plus minocycline for 7 days. Researchers will check if more people regain independence 6…

This study tests whether combining a small surgery to remove blood clots from the brain with a drug called deferoxamine can help people recover better after a brain bleed. About 240 adults aged 18 to 80 with moderate to severe bleeding will be randomly assigned to get the combo t…

This study tests a drug called tenecteplase (TNK) for treating intracerebral hemorrhage, a type of stroke caused by bleeding in the brain. The drug is injected directly into the blood clot through a thin tube during standard surgery. The main goal is to check if TNK is safe and h…

This study tests if using a special thermometer in the bladder to guide body temperature control helps people recover from a severe bleeding stroke. About 308 adults with deep coma will be randomly assigned to either this new method or standard armpit temperature checks. The main…

This study tests a traditional Chinese medicine called Calculus Bovis Sativus (CBS) in 300 people who have had a brain hemorrhage (bleeding in the brain). CBS is made from bezoar ingredients and is thought to reduce inflammation and protect brain cells. Participants will take CBS…

This study tests a new blood test (GFAP) used in ambulances to quickly tell if a stroke patient has a brain bleed. About 465 adults with stroke symptoms will be tested within 3 hours. The goal is to see if the test can accurately rule out brain bleeding before reaching the hospit…

This early study tests whether a 7-day continuous IV drip of propranolol, a common heart medication, can safely prevent pneumonia in adults who have had a severe brain bleed. The trial will enroll 30 participants within 24 hours of their stroke. The main goals are to find the saf…

This study uses blood samples from healthy people and those with bleeding disorders to create artificial blood clots in the lab. Researchers will test different doses of a clot-busting drug to see which works best for each condition. The goal is to improve future treatments for b…

This study will collect detailed information from 200 adults with severe brain injuries treated at Örebro University Hospital. Researchers will track their recovery over 12 months using medical records and follow-up data. The goal is to better understand how brain injuries progre…

This study looks at how inflammation and blood-brain barrier damage affect recovery after a type of stroke called intracerebral hemorrhage. About 117 adults will get special brain scans and blood tests 10 days after their stroke. The goal is to see if these measures can predict w…

This study looks at how air moves in the lungs of brain-injured patients when doctors are trying to take them off a breathing machine. Using a special imaging belt (electrical impedance tomography), researchers will track changes in lung ventilation patterns. The goal is to find …

This study aims to understand if specific markers on brain scans can better predict which patients with brain hemorrhage face higher risks of death or disability. Researchers will compare scan findings with existing prediction methods in 50 participants. The goal is to improve ri…