INTRACEREBRAL HEMORRHAGE

This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) can reduce brain swelling and improve recovery in people who have had a bleeding stroke. About 200 adults with a specific type of brain bleed will receive either standard care or the drug plus standar…

This study looks at whether starting blood thinners (DOACs) is safe and effective for people who have had a stroke, but also have a history of a brain bleed and an irregular heartbeat (atrial fibrillation). About 852 participants will be randomly assigned to receive either a bloo…

This early-phase study tests whether a drug called Tenecteplase (TNK) is safe to inject directly into a brain bleed (intracerebral hemorrhage). Five adults aged 18-80 with large bleeds will receive a single dose during standard surgery. The goal is to see if TNK can dissolve the …

This study tests if the antibiotic minocycline can improve recovery after a brain bleed (intracerebral hemorrhage). About 1,248 patients will either receive standard care or standard care plus minocycline for 7 days. Researchers will check their ability to function independently …

This study tests whether combining minimally invasive surgery with a drug called deferoxamine helps people recover better after a brain hemorrhage. The surgery removes the blood clot, while the drug may protect brain cells. About 240 adults with moderate to severe bleeding will b…

This study tests whether a lab-made version of bezoar, called Calculus Bovis Sativus (CBS), can help people recover from a brain hemorrhage. 300 participants will take CBS or natural bezoar pills for 7 days. Researchers will measure recovery using standard stroke scales and brain…

This study tests a rapid blood test (GFAP) that paramedics can use in ambulances to quickly identify if a stroke patient has a brain bleed. The test aims to help doctors decide the best treatment faster. About 465 adults with stroke symptoms will be enrolled within 3 hours of sym…

This early study tests the safety of a 7-day intravenous drip of propranolol (a drug usually used for heart conditions) to prevent pneumonia in 30 adults who have had a severe brain bleed. The goal is to find the best dose and see if it reduces lung infections. Participants must …

This study tests whether a virtual home rehabilitation program helps stroke survivors in underserved Texas communities recover better than standard care alone. About 80 adults who recently had a stroke and are returning home will take part. The program uses video sessions to guid…

This study will measure certain proteins in the blood of people who have had a brain hemorrhage (bleeding in the brain) and compare them to healthy volunteers. The goal is to see if these proteins are linked to inflammation after the bleed. No drugs or treatments are being tested…

This observational study will follow 2,500 people who had a brain hemorrhage and received minimally invasive surgery. Researchers want to see how well patients recover in real-world settings. The study does not test a new drug or procedure, but gathers data to improve future care…

This study will test a new tool called the Stroke Mimics Score (SMS) in 1000 adults who come to the emergency room with stroke-like symptoms. The goal is to see if the SMS can accurately tell the difference between a real stroke and a condition that looks like a stroke but isn't …

This study looks at 117 people who had a brain bleed (intracerebral hemorrhage) to understand how inflammation and damage to the brain's protective barrier affect recovery. Participants will get special brain scans and blood tests about 10 days after the bleed. The goal is to lin…

This study tests a new way to recruit women into stroke research using easy-to-understand materials like brochures and videos. Researchers will compare this approach to usual recruitment methods with 1,600 participants. The goal is to make stroke studies more inclusive so treatme…

This study tests a 5-week support program for stroke survivors after they leave the hospital. The goal is to see if the program helps them feel more confident and independent in managing their daily health. Researchers will compare participants who get the program plus usual care…

This study looks at how air moves in the lungs of brain-injured patients when doctors are removing their breathing tube. Using a special imaging belt (electrical impedance tomography), researchers will track changes in lung ventilation patterns. The goal is to find patterns that …

This study will collect detailed information from 200 adults with severe brain injuries treated at Örebro University Hospital. Researchers will track their recovery, including brain function and healthcare needs, for up to a year. No new treatments are being tested—the goal is to…

This study will follow 50 people with brain hemorrhage to see if a feature called the 'spot sign' on CT scans can predict who is at higher risk of death or disability. Researchers will compare these scan findings with standard risk scores. The goal is to improve early identificat…