INSULIN SENSITIVITY

This study looked at whether a type of talk therapy (cognitive-behavioral therapy) could improve how the body uses insulin in teenage girls at risk for type 2 diabetes. The 147 participants were girls aged 12-17 with overweight or obesity, mild to moderate depression, and a famil…

This study tested whether removing sugary drinks from workplace cafeterias and offering brief counseling could help employees lose belly fat and improve insulin sensitivity. Over 600 full-time hospital workers who drank at least three sugary beverages per week took part. Research…

This study tested a 12-week diet and exercise program in 40 older adults with insulin resistance and apathy, a motivation disorder. Participants received all meals and supervised exercise. The goal was to see if the program improves insulin sensitivity and reduces apathy, and whe…

This study looked at how drinking orange juice compared to a sugar-sweetened beverage affects risk factors for heart disease and type 2 diabetes. Fifty-six adults drank either orange juice or a sugary drink for four weeks. Researchers measured changes in cholesterol, blood sugar,…

This completed early-phase study tested different doses of fatty acids (Intralipid) in 9 healthy volunteers to find the dose that causes mild insulin resistance. The goal was to create a reliable model for future diabetes research. Participants received low or medium doses of fat…

This study looked at how regular aerobic exercise changes appetite and metabolism in sedentary overweight teenagers. Researchers measured hunger levels and blood markers after a meal, comparing teens who exercised with those who didn't. The goal is to understand if exercise alone…

This study looked at how exercise changes certain fat molecules called PAHSAs, which help the body use insulin better. Researchers measured PAHSA levels in blood and fat tissue from 60 healthy people of different ages and body sizes before and after exercise. The goal was to unde…

This study looked at whether the diabetes drug metformin can slow aging in people without diabetes. Researchers wanted to see if the drug's effects depend on whether a person is insulin sensitive or insulin resistant. Over 12 weeks, 101 adults aged 40-75 took either metformin or …

This study looked at how drinking beverages with different sweeteners—low-calorie sucralose, refined sugar, or natural fruit juice—affects blood sugar control and gut health in healthy adults. Over three weeks, 42 participants drank one type of sweetened drink daily. Researchers …