INFLAMMATORY BOWEL DISEASE
Clinical trials for INFLAMMATORY BOWEL DISEASE explained in plain language.
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Could a common arthritis drug help PSC patients?
Disease control CompletedThis study tested whether sulfasalazine, a drug used for arthritis, can improve liver health and symptoms in people with primary sclerosing cholangitis (PSC) who also have inflammatory bowel disease. 32 adults across the US took either the drug or a placebo for a set time. Resear…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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App-Based monitoring shows promise for IBD patients
Disease control CompletedThis study tested a web-based telemonitoring system called TECCU for people with moderate-to-severe inflammatory bowel disease (Crohn's disease or ulcerative colitis). 290 participants in Spain were randomly assigned to use the app or receive usual care. The goal was to see if th…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: NA • Sponsor: Grupo Espanol de Trabajo en Enfermedad de Crohn y Colitis Ulcerosa • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Can a team approach help IBD patients with anxiety and depression?
Disease control CompletedThis study tested two team-based care models for 657 adults with inflammatory bowel disease (Crohn's or ulcerative colitis) who also had mild to severe behavioral health symptoms. One model used in-person visits with a team including a gastroenterologist, nurse, nutritionist, and…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: NA • Sponsor: University of Pittsburgh • Aim: Disease control
Last updated Jun 26, 2026 13:18 UTC
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Could relaxation techniques ease gut disorders? new study investigates
Symptom relief CompletedThis study tests whether a 9-week relaxation response mind-body program can improve quality of life and reduce symptoms in people with irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). Participants attend weekly group sessions that include breathing exercises, m…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jul 01, 2026 23:00 UTC
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New recovery plan may get kids home faster after bowel surgery
Symptom relief CompletedThis study tested a 21-step enhanced recovery protocol for children aged 10-18 undergoing elective gastrointestinal surgery. The protocol included things like shorter fasting times, early eating and moving, and less use of opioids. The goal was to see if it could shorten hospital…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: PHASE3 • Sponsor: Northwestern University • Aim: Symptom relief
Last updated Jun 27, 2026 14:03 UTC
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Bridge device for stoma: does it help or hinder?
Symptom relief CompletedThis study looked at whether placing a bridge device during loop ileostomy creation reduces complications like infections or stoma problems. 166 adults having elective colorectal surgery took part. The goal was to see if the device improves outcomes or just adds difficulty to car…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New nursing approach eases anxiety after colostomy surgery
Symptom relief CompletedThis study tested a 12-week nursing program based on the Roy Adaptation Model for adults who recently had a colostomy. It aimed to reduce anxiety and depression and improve quality of life compared to standard care. 115 participants were randomly assigned to either the special pr…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: NA • Sponsor: West China Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Could a special liquid diet soothe IBD in rare immune disease?
Symptom relief CompletedThis study tested whether a liquid diet called Neocate Splash could change gut bacteria and ease stomach symptoms in people with chronic granulomatous disease (CGD) and inflammatory bowel disease (IBD). Three participants followed the diet for up to 4 weeks, with hospital stays a…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Scientists investigate gut-healing protein in Crohn's and colitis
Knowledge-focused CompletedThis study looked at how a protein called IL-22 binding protein (IL-22BP) affects gut healing in people with Crohn's disease or ulcerative colitis. Researchers compared samples from 52 patients and healthy volunteers to understand how IL-22BP is regulated during disease flares. T…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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IBD patients at risk for eating disorders, study finds
Knowledge-focused CompletedThis study measured how often adults with inflammatory bowel disease (Crohn's disease or ulcerative colitis) show signs of eating disorders, including avoidant/restrictive food intake disorder (ARFID). Researchers used questionnaires to assess eating habits and nutritional status…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: Federico II University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Can exercise strengthen bones in children with IBD?
Knowledge-focused CompletedThis study looked at 84 children and teens with inflammatory bowel disease (IBD) to see if daily physical activity is linked to better bone density. Participants wore activity monitors and had bone scans. The goal is to understand if staying active could help prevent bone loss, a…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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New study checks if IBD drug skyrizi seeps into breast milk
Knowledge-focused CompletedThis study looked at how much of the drug risankizumab (Skyrizi) passes into the breast milk of women with inflammatory bowel disease (IBD). Ten breastfeeding mothers who were already taking the drug provided milk samples over several weeks. The goal is to understand potential ex…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: PHASE4 • Sponsor: AbbVie • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Stool tests could make IBD monitoring easier and cheaper
Knowledge-focused CompletedThis study looked at 120 adults with inflammatory bowel disease (IBD) to see if simple stool tests can tell if the disease is active or in remission, just like a colonoscopy does. Colonoscopy is the current gold standard but is expensive, invasive, and not ideal for frequent chec…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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New antibody tested in healthy volunteers – no cure yet
Knowledge-focused CompletedThis early-stage study tested a single dose of the experimental antibody SM17 in 30 healthy Chinese adults to see if it is safe and how the body processes it. The study did not aim to treat any disease. Results will help plan future trials for conditions like eczema, asthma, and …
Matched conditions: INFLAMMATORY BOWEL DISEASE
Phase: PHASE1 • Sponsor: SinoMab BioScience Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Study reveals HPV vaccine gaps in teens with chronic illness
Knowledge-focused CompletedThis study looked at how many girls and young women aged 11 to 20 with chronic diseases (like diabetes or immune conditions) got the HPV vaccine, compared to those without chronic illness. Researchers reviewed records of 223 participants from a hospital in France. The goal was to…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Kids' laxative study reveals how body handles the drug
Knowledge-focused CompletedThis study measured levels of the laxative PEG 3350 and its breakdown products in the blood and urine of 158 children who were already taking it, compared to children not taking it. The goal was simply to learn how the body processes this medicine, not to change any treatments. R…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: Children's Hospital of Philadelphia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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Silent gut narrowings in Crohn's: to treat or not to treat?
Knowledge-focused CompletedThis study looked at 150 adults with Crohn's disease who had narrowings in the small intestine (strictures) but no symptoms. Researchers reviewed medical records to see how often these silent strictures later caused problems like belly pain, nausea, or vomiting. The goal is to he…
Matched conditions: INFLAMMATORY BOWEL DISEASE
Sponsor: University Medical Center Zvezdara • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:35 UTC