HYPOSPADIAS
Clinical trials for HYPOSPADIAS explained in plain language.
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Pee power: urine stem cells may fix penile defects in kids
Disease control CompletedThis study tested a new approach to reduce complications in boys born with hypospadias, a condition where the urinary opening is on the underside of the penis. Researchers used exosomes (tiny healing particles) from the boys' own urine stem cells during surgery to help rebuild th…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Shanghai Children's Hospital • Aim: Disease control
Last updated May 17, 2026 03:53 UTC
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Second-Time fix for birth defect shows promise in small study
Disease control CompletedThis study tested a single-stage surgery called tubularized incised plate urethroplasty for children who needed a second hypospadias repair. Fifteen children with a suitable urethral plate took part. The goal was to see how successful the surgery was and to track complications li…
Matched conditions: HYPOSPADIAS
Sponsor: Tanta University • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New study tests better surgical fix for boys born with penis opening in wrong spot
Disease control CompletedThis study looked at 120 boys aged 2-12 who had surgery to correct distal hypospadias, a birth defect where the urine opening is not at the tip of the penis. Doctors compared two surgical techniques: one using a standard double-layer tissue cover, and another adding an extra flap…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Javaid Afridi • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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New study finds best pain relief for young boys after surgery
Symptom relief CompletedThis study looked at 86 children, ages 1 to 7, having surgery for hypospadias (a birth condition affecting the penis). Researchers compared two types of pain blocks given during surgery: a sacral erector spinae plane block and a caudal epidural block. Pain was measured using a sp…
Matched conditions: HYPOSPADIAS
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated May 17, 2026 04:01 UTC
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New pain block study aims to improve comfort for kids after penile surgery
Symptom relief CompletedThis study tested two different ultrasound-guided pain blocks in 30 children aged 1-7 years having hypospadias repair surgery. The goal was to see which block provides longer pain relief after surgery. Researchers measured the time until the first rescue pain medication was neede…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Which nerve block eases kids' surgery pain better? new study investigates.
Symptom relief CompletedThis study looked at 60 children aged 1 to 6 having hypospadias surgery. It compared two types of nerve blocks given with general anesthesia to see which provides better pain relief after surgery. The goal is to improve how we manage pain in young children after this common opera…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Estrogen cream may help boys heal better after penis surgery
Symptom relief CompletedThis study tested whether applying estrogen cream to the penis daily for two months before surgery could reduce complications like fistulas (abnormal openings) and wound separation in 244 boys with severe hypospadias, a birth defect where the urethra doesn't form properly. The bo…
Matched conditions: HYPOSPADIAS
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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Study reveals best urine drainage method after penile surgery
Knowledge-focused CompletedThis study looked at 86 children who had surgery to fix a common birth defect where the urine opening is on the underside of the penis (distal hypospadias). The goal was to find the best method and length of time for draining urine after surgery to prevent complications like fist…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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Study tests if skipping stent reduces leaks after penile surgery in boys
Knowledge-focused CompletedThis study looked at 110 boys aged 1-12 years having surgery for hypospadias, a birth defect where the urine opening is on the underside of the penis. Surgeons compared two approaches: leaving a temporary tube (stent) in the new urine passage after surgery versus no stent. The go…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Children's Hospital and Institute of Child Health, Multan • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Penile size study seeks answers for hypospadias surgery
Knowledge-focused CompletedThis study measured the size of the glans (head of the penis) in 410 boys undergoing urologic surgery, comparing those with hypospadias to those without. The goal was to collect data by age, weight, and ethnicity to understand normal growth differences. No treatment was given; it…
Matched conditions: HYPOSPADIAS
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Gene hunt for common birth defect
Knowledge-focused CompletedThis study looked for new genes that may cause hypospadias, a birth defect where the opening of the penis is not at the tip. Researchers studied 60 people who have hypospadias and a family history of the condition. They used exome sequencing to compare genomes and find genetic va…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated May 04, 2026 16:19 UTC
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10 men revisited years after childhood penile surgery
Knowledge-focused CompletedThis study looked at 10 males who had surgery for hypospadias (a birth defect where the urine opening is not at the tip of the penis) during childhood. The goal was to see how they were doing after puberty, checking for complications, urinary symptoms, and sexual function. Resear…
Matched conditions: HYPOSPADIAS
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:05 UTC