HYPOSPADIAS
Clinical trials for HYPOSPADIAS explained in plain language.
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Hormone cream could reduce complications in common birth defect surgery
Disease control CompletedThis study tested whether applying an estrogen cream to the penis for two months before surgery could help reduce healing complications in boys with severe hypospadias. Researchers compared the estrogen cream against a placebo cream in 244 boys aged 9-36 months who needed surgica…
Matched conditions: HYPOSPADIAS
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Study aims to reduce complications in common childhood surgery
Disease control CompletedThis study compared two different ways to drain urine after surgery to correct a common birth defect in boys called hypospadias. It involved 86 boys with a mild form of the condition to see which drainage method and how long it was used led to fewer problems, like urine leaks, af…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Child's own cells tested to fix common birth defect, reduce surgery complications
Disease control CompletedThis study tested whether adding tiny particles from a child's own stem cells could help rebuild missing tissue during surgery for a common birth defect called hypospadias. The goal was to see if this new approach could lower the high rate of complications like fistulas and stric…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Shanghai Children's Hospital • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Second chance surgery for birth defect repair shows promise
Disease control CompletedThis study looked at a specific surgical technique for children who needed a second operation to correct hypospadias, a birth defect where the urethra doesn't fully develop. Doctors tested if a single-stage procedure could successfully rebuild the urinary channel in these complex…
Matched conditions: HYPOSPADIAS
Sponsor: Tanta University • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Study seeks best way to fix common birth defect in boys
Disease control CompletedThis study compared two standard surgical techniques for repairing hypospadias, a birth condition where the opening of the penis is in the wrong place. It involved 110 boys aged 1-12 years to see if leaving a small temporary tube (a stent) in place after surgery leads to fewer co…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Children's Hospital and Institute of Child Health, Multan • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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New pain block tested for Kids' surgery
Symptom relief CompletedThis study compared two different ultrasound-guided nerve-blocking techniques for managing pain in children (aged 1-7 years) undergoing hypospadias repair surgery. The goal was to see if a newer method, called a sacral multifidus plane block, works as well as or better than the s…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New pain block tested against standard for Kids' surgery
Symptom relief CompletedThis study compared two methods for managing pain after hypospadias repair surgery in young children. Researchers tested a newer nerve block technique against the standard epidural block to see which provided better pain relief. They measured pain levels in 86 children aged 1 to …
Matched conditions: HYPOSPADIAS
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated Mar 30, 2026 14:30 UTC
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Scientists hunt for hidden genes behind common birth defect
Knowledge-focused CompletedThis study aimed to discover new genes that cause hypospadias, a condition where the opening of the urethra is not at the tip of the penis. Researchers analyzed the DNA of 60 patients from families with multiple cases of hypospadias. The goal was to improve understanding of the c…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Apr 02, 2026 02:26 UTC
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Doctors track boys for years after penis repair surgery
Knowledge-focused CompletedThis study followed 10 boys who had surgery to correct hypospadias, a common birth defect where the opening of the urethra is not at the tip of the penis. Researchers checked on their health after puberty to see how well the surgical repairs held up over the long term. They looke…
Matched conditions: HYPOSPADIAS
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Landmark study measures Boys' penis size to improve surgery
Knowledge-focused CompletedThis study measured the size of the penis and glans (head) in boys with hypospadias, a birth defect where the urethra opening is in the wrong place, and compared them to boys without the condition. Researchers took detailed measurements from 410 boys during their urological surge…
Matched conditions: HYPOSPADIAS
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated Mar 16, 2026 15:24 UTC