HYPOSPADIAS
Clinical trials for HYPOSPADIAS explained in plain language.
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New study tests better way to fix a common birth defect in boys
Disease control CompletedThis study compared two surgical methods for repairing distal hypospadias, a birth defect where the urinary opening is on the underside of the penis. 120 boys aged 2-12 received either a standard double dartos flap or that plus a Byar's flap. The goal was to see which technique l…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Javaid Afridi • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Urine-derived stem cell therapy shows promise for reducing surgery complications in boys with hypospadias
Disease control CompletedThis study tested whether stem cell exosomes from a boy's own urine could improve healing after surgery for hypospadias, a common birth defect where the urethra opening is not at the tip of the penis. 82 boys with severe hypospadias were split into two groups: one received standa…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Shanghai Children's Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Second-Time fix for a birth defect shows promise in small study
Disease control CompletedThis study looked at a single surgery to correct hypospadias in children who had already had one repair. Hypospadias is a birth defect where the opening of the urethra is not at the tip of the penis. The surgery used a technique called tubularized incised plate urethroplasty. The…
Matched conditions: HYPOSPADIAS
Sponsor: Tanta University • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Estrogen cream may cut surgery complications in boys with birth defect
Disease control CompletedThis study tested whether applying estrogen cream to the penis for two months before surgery reduces complications in boys with severe hypospadias, a birth defect where the urethra opening is not at the tip. 244 boys aged 9-36 months received either estrogen cream or a placebo cr…
Matched conditions: HYPOSPADIAS
Phase: PHASE3 • Sponsor: Hospices Civils de Lyon • Aim: Disease control
Last updated Jun 26, 2026 13:53 UTC
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Which nerve block works best for kids' post-surgery pain?
Symptom relief CompletedThis study compared two types of ultrasound-guided nerve blocks (caudal block and dorsal penile block) to control pain after hypospadias repair in 62 boys aged 1-6 years. The main goal was to see how long it took before children needed extra pain medicine. The results could help …
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ahmed Aouf • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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New study seeks best pain relief for kids after hypospadias surgery
Symptom relief CompletedThis study tested two types of nerve blocks to see which provides better pain relief for children aged 1 to 6 after hypospadias surgery. Sixty kids received either a pudendal nerve block or a dorsal penile nerve block, both guided by ultrasound. Researchers measured pain levels a…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Bangladesh Medical University • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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New pain block tested for kids' surgery: could it replace the standard?
Symptom relief CompletedThis study tested two ways to numb the lower back for pain relief in 30 children having hypospadias repair. One method targets the multifidus muscle, the other the caudal space. The goal was to see which provides longer pain relief after surgery.
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Study finds best way to drain urine after penile surgery in boys
Symptom relief CompletedThis study looked at 86 children who had surgery to fix a common birth defect where the urine opening is on the underside of the penis (distal hypospadias). The goal was to find the best way and length of time to drain urine after surgery to prevent a leak (fistula). Researchers …
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Which pain block works best for kids after hypospadias repair?
Symptom relief CompletedThis study looked at 86 children aged 1-7 years having hypospadias repair. Researchers compared two pain-block methods: a sacral erector spinae plane block and a caudal epidural block. Both used the same numbing medicine. Pain was measured for 24 hours after surgery to see which …
Matched conditions: HYPOSPADIAS
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Kids' Pre-Op anxiety linked to worse recovery, study finds
Knowledge-focused CompletedThis study looked at 114 boys aged 2 to 7 having urogenital surgery to see if being anxious before the operation leads to more pain or confusion after waking up. Researchers measured anxiety before surgery and then tracked pain, delirium, and recovery speed in the recovery room. …
Matched conditions: HYPOSPADIAS
Sponsor: Aydin Adnan Menderes University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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10 men revisited years after hypospadias Repair—What happened?
Knowledge-focused CompletedThis study followed 10 males who had surgery for hypospadias (a birth defect where the urine opening is on the underside of the penis) to see how they fared long after puberty. Researchers performed physical exams, bladder and testicle ultrasounds, and blood tests to check for co…
Matched conditions: HYPOSPADIAS
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Stent or no stent? study seeks best way to prevent leaks after penile surgery
Knowledge-focused CompletedThis study looked at 110 boys aged 1-12 years having surgery for hypospadias, a birth condition where the urine opening is on the underside of the penis. Half had a temporary tube (stent) placed after surgery, half did not. Researchers checked for a common complication called a f…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: Children's Hospital and Institute of Child Health, Multan • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Researchers measure penis size in boys with and without hypospadias
Knowledge-focused CompletedThis study measured the size of the glans (head of the penis) and total penile length in 410 boys undergoing urological surgery. Some had hypospadias (a birth defect where the urinary opening is not at the tip), others had other conditions. The goal was to see if glans size diffe…
Matched conditions: HYPOSPADIAS
Sponsor: Albany Medical College • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC
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DNA hunt for hidden genes in common birth defect
Knowledge-focused CompletedThis study looked at 60 people with a family history of hypospadias, a birth defect where the opening of the penis is not at the tip. Researchers used DNA sequencing to find new genetic changes linked to the condition. The goal was to discover genes that may cause hypospadias whe…
Matched conditions: HYPOSPADIAS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC